Phenolic components from the leaves of Panax ginseng and their effects on HL-60 human leukemia cells

被引：0
|
作者：
Nguyen Huu Tung
Jeong-Hyun Son
Kyoungwon Cho
Jeong-Ah Kim
Jae-Hee Hyun
Hee-Kyoung Kang
Gyu Yong Song
Chun Jung Park
Young Ho Kim
机构：
[1] Chungnam National University,College of Pharmacy
[2] Jeju National University,School of Medicine, Institute of Medical Sciences
[3] Geumsan Ginseng Cooperative Association,undefined
来源：
Food Science and Biotechnology | 2010年 / 19卷
关键词：
Araliaceae; flavonoid; cytotoxic activity; HL-60 cell; apoptosis;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
This study investigates phenolic components from the Panax ginseng C.A. Meyer leaves led to the isolation of 3 flavonoids (1–3). Their structures were characterized on the basis of physicochemical properties, nuclear magnetic resonance (NMR) spectra, electron spray ionization-mass spectrometry (ESI-MS) data, and comparison with those in the literature. Of them, sophoraflavonoloside (2) and prunin (3) were found to inhibit the growth of HL-60 human leukemia cells with IC50 in values of 29.8 and 21.4 μM by the induction of apoptosis.
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页码：271 / 274
页数：3
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