severe hypobaric hypoxia;
reoxygenation;
lipid peroxidation;
hippocampus;
neocortex;
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摘要:
We studied the effects of severe hypobaric hypoxia followed by reoxygenation at the level and the time course of changes in free radical lipid oxidation in the hippocampus, neocortex, and mitochondriaenriched neocortical fraction of rats. We found that severe hypobaric hypoxia induced long-term changes in lipid peroxidation in the brain structures susceptible to hypoxia, the hippocampus and the neocortex.
机构:
Department of Morphology, Institute of Experimental Medicine, Russian Academy of Medical Sciences, St. PetersburgDepartment of Morphology, Institute of Experimental Medicine, Russian Academy of Medical Sciences, St. Petersburg
Khozhai L.I.
Otellin V.A.
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机构:
Department of Morphology, Institute of Experimental Medicine, Russian Academy of Medical Sciences, St. PetersburgDepartment of Morphology, Institute of Experimental Medicine, Russian Academy of Medical Sciences, St. Petersburg
Otellin V.A.
Kostkin V.B.
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机构:
Department of Morphology, Institute of Experimental Medicine, Russian Academy of Medical Sciences, St. PetersburgDepartment of Morphology, Institute of Experimental Medicine, Russian Academy of Medical Sciences, St. Petersburg