EFEMP2 upregulates PD-L1 expression via EGFR/ERK1/2/c-Jun signaling to promote the invasion of ovarian cancer cells

被引:0
|
作者
Xin Shen
Xuli Jin
Shuang Fang
Jie Chen
机构
[1] Shandong University,Department of Maternal and Child Health, School of Public Health, Cheeloo College of Medicine
[2] Shandong University,Department of Epidemiology, School of Public Health, Cheeloo College of Medicine
[3] Jinan Medical Center Management Committee,undefined
关键词
Ovarian cancer; EFEMP2; PD-L1; EGFR; ERK1/2/c-Jun pathway; Trametinib; Afatinib;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [41] GPR12 Inhibits Apoptosis in Epithelial Ovarian Cancer via the Activation of ERK1/2 Signaling
    Wang, Lu
    Yang, Da
    Zhang, Yao
    Jiao, Yisheng
    FRONTIERS IN ONCOLOGY, 2022, 12
  • [42] PD-1, PD-L1 and PD-L2 expression in mouse prostate cancer
    Yang, Shijie
    Zhang, Qiuyang
    Liu, Sen
    Wang, Alun R.
    You, Zongbing
    AMERICAN JOURNAL OF CLINICAL AND EXPERIMENTAL UROLOGY, 2016, 4 (01): : 1 - 8
  • [43] In vitro effect of Pannexin 1 channel on the invasion and migration of I-10 testicular cancer cells via ERK1/2 signaling pathway
    Liu, Haofeng
    Yuan, Min
    Yao, Yanxue
    Wu, Dandan
    Dong, Shuying
    Tong, Xuhui
    BIOMEDICINE & PHARMACOTHERAPY, 2019, 117
  • [44] Folate receptor alpha is associated with cervical carcinogenesis and regulates cervical cancer cells growth by activating ERK1/2/c-Fos/c-Jun
    Liu, Chunliang
    Ding, Ling
    Bai, Lixia
    Chen, Xiao
    Kang, Huijie
    Hou, Lifang
    Wang, Jintao
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2017, 491 (04) : 1083 - 1091
  • [45] L1CAM is involved in lymph node metastasis via ERK1/2 signaling in colorectal cancer
    Fang, Qing-Xia
    Zheng, Xiao-Chun
    Zhao, Hua-Jun
    AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH, 2020, 12 (03): : 837 - 846
  • [46] Clinical and Prognostic Value of Antigen-Presenting Cells with PD-L1/PD-L2 Expression in Ovarian Cancer Patients
    Pawlowska, Anna
    Kwiatkowska, Agnieszka
    Suszczyk, Dorota
    Chudzik, Agata
    Tarkowski, Rafal
    Barczynski, Bartlomiej
    Kotarski, Jan
    Wertel, Iwona
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 22 (21)
  • [47] Acquired resistance to EGFR-TKI upregulates the expression of PD-L1 and promotes immune escape in lung cancer
    Peng, Shunli
    Li, Qi
    Wang, Wei
    CANCER RESEARCH, 2017, 77
  • [48] Absence of PD-L1 on tumor cells is associated with reduced MHC I expression and PD-L1 expression increases in recurrent serous ovarian cancer
    Aust, Stefanie
    Felix, Sophie
    Auer, Katharina
    Bachmayr-Heyda, Anna
    Kenner, Lukas
    Dekan, Sabine
    Meier, Samuel M.
    Gerner, Christopher
    Grimm, Christoph
    Pils, Dietmar
    SCIENTIFIC REPORTS, 2017, 7
  • [49] Interleukin-22 upregulates FIB-EGF expression in HaCat cells via JAK2/STAT3 and ERK1/2 signaling
    Luo, S.
    Liu, X.
    Zheng, Y.
    Xu, W.
    Ni, H.
    Li, Y.
    Liu, Q.
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2015, 135 (08) : S5 - S5
  • [50] Absence of PD-L1 on tumor cells is associated with reduced MHC I expression and PD-L1 expression increases in recurrent serous ovarian cancer
    Stefanie Aust
    Sophie Felix
    Katharina Auer
    Anna Bachmayr-Heyda
    Lukas Kenner
    Sabine Dekan
    Samuel M. Meier
    Christopher Gerner
    Christoph Grimm
    Dietmar Pils
    Scientific Reports, 7