Antileukemic effect of venetoclax and hypomethylating agents via caspase-3/GSDME-mediated pyroptosis

被引：0
|
作者：
Fanghua Ye
Wen Zhang
Chenying Fan
Jiajia Dong
Min Peng
Wenjun Deng
Hui Zhang
Liangchun Yang
机构：
[1] Xiangya Hospital,Department of Pediatrics
[2] Central South University,undefined
来源：
Journal of Translational Medicine | / 21卷 / 1期
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [41] Pharmacological inhibition of cGAS ameliorates postoperative cognitive dysfunction by suppressing caspase-3/GSDME-dependent pyroptosis
    Bu, Xueshan
    Gong, Ping
    Zhang, Lei
    Song, Wenqin
    Hou, Jiabao
    Li, Qingwen
    Wang, Wei
    Xia, Zhongyuan
    NEUROCHEMISTRY INTERNATIONAL, 2024, 178
  • [42] Germacrone induces caspase-3/GSDME activation and enhances ROS production, causing HepG2 pyroptosis
    Sun, Xinfeng
    Zhong, Xin
    Ma, Wenfeng
    Feng, Wenxing
    Huang, Qi
    Ma, Mengqing
    Lv, Minling
    Hu, Rui
    Han, Zhiyi
    Li, Jing
    Zhou, Xiaozhou
    EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2022, 24 (01)
  • [43] Inhibition of PINK1-Mediated Mitophagy Contributes to Postoperative Cognitive Dysfunction through Activation of Caspase-3/GSDME-Dependent Pyroptosis
    Wang, Wei
    Zhao, Bo
    Gao, Wenwei
    Song, Wenqin
    Hou, Jiabao
    Zhang, Lei
    Xia, Zhongyuan
    ACS CHEMICAL NEUROSCIENCE, 2023, 14 (07): : 1249 - 1260
  • [44] Decitabine combined with cold atmospheric plasma induces pyroptosis via the ROS/Caspase-3/GSDME signaling pathway in Ovcar5 cells
    Du, Liang
    Ming, Huiyun
    Yan, Zhuna
    Chen, Jinwu
    Song, Wencheng
    Dai, Haiming
    BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2024, 1868 (06):
  • [45] Shikonin triggers GSDME-mediated pyroptosis in tumours by regulating autophagy via the ROS-MAPK14/p38α axis
    Ju, Xiaoli
    Zhang, Heng
    Wang, Jiayou
    Sun, Zhonghe
    Guo, Lanfang
    Wang, Qiang
    PHYTOMEDICINE, 2023, 109
  • [46] HDAC11 promotes both NLRP3/caspase-1/GSDMD and caspase-3/GSDME pathways causing pyroptosis via ERG in vascular endothelial cells
    Yao, Feng
    Jin, Zhen
    Zheng, Zihan
    Lv, Xiaohan
    Ren, Lingxuan
    Yang, Jianjun
    Chen, Danli
    Wang, Bo
    Yang, Wei
    Chen, Lifang
    Wang, Weirong
    Gu, Jianli
    Lin, Rong
    CELL DEATH DISCOVERY, 2022, 8 (01)
  • [47] Anagrelide and idarubicin combination induces GSDME-mediated pyroptosis as a potential therapy for high-PDE3A acute myeloid leukemia
    Yang, Chenwei
    Hu, Yixin
    Gao, Li
    Li, Zhiheng
    Zhang, Yongping
    Zhuo, Ran
    Du, Yayun
    Liu, Hu
    Ji, Qi
    Liu, Minyuan
    Pan, Jian
    Lu, Jun
    Xiao, Peifang
    Tian, Yuanyuan
    He, Sudan
    Ling, Jing
    Hu, Shaoyan
    LEUKEMIA, 2025, 39 (01) : 98 - 111
  • [48] Metformin activates AMPK/SIRT1/NF-κB pathway and induces mitochondrial dysfunction to drive caspase3/GSDME-mediated cancer cell pyroptosis
    Zheng, Zhaodi
    Bian, Yan
    Zhang, Yang
    Ren, Guanghui
    Li, Guorong
    CELL CYCLE, 2020, 19 (10) : 1089 - 1104
  • [49] HDAC11 promotes both NLRP3/caspase-1/GSDMD and caspase-3/GSDME pathways causing pyroptosis via ERG in vascular endothelial cells
    Feng Yao
    Zhen Jin
    Zihan Zheng
    Xiaohan Lv
    Lingxuan Ren
    Jianjun Yang
    Danli Chen
    Bo Wang
    Wei Yang
    Lifang Chen
    Weirong Wang
    Jianli Gu
    Rong Lin
    Cell Death Discovery, 8
  • [50] Cisplatin induces acute liver injury by triggering caspase-3/GSDME-me diate d cell pyroptosis
    PingPing Wu
    XiuJin Shen
    ShuSen Zheng
    Hepatobiliary & Pancreatic Diseases International, 2025, 24 (02) : 177 - 187
12345