Simvastatin plus irinotecan, 5-fluorouracil, and leucovorin (FOLFIRI) as first-line chemotherapy in metastatic colorectal patients: a multicenter phase II study

被引：0
|
作者：
Jeeyun Lee
Kyung Hae Jung
Young Suk Park
Joong Bae Ahn
Sang Jun Shin
Seock-Ah Im
Do Youn Oh
Dong Bok Shin
Tae Won Kim
Namsu Lee
Jae Ho Byun
Yong Sang Hong
Joon Oh Park
Se Hoon Park
Ho Yeong Lim
Won Ki Kang
机构：
[1] Sungkyunkwan University School of Medicine,Division of Hematology
[2] Research Institute and Hospital,Oncology, Department of Medicine, Samsung Medical Center
[3] Yonsei University College of Medicine,Center for Colorectal Cancer, National Cancer Center
[4] Seoul National University College of Medicine,Department of Internal Medicine
[5] Gachon University Gil Medical Center,Department of Internal Medicine
[6] University of Ulsan College of Medicine,Division of Hematology and Oncology, Department of Internal Medicine
[7] Soon Chun Hyang University Hospital,Division of Oncology, Department of Medicine, Asan Medical Center
[8] The Catholic University of Korea,Division of Hematology
来源：
Cancer Chemotherapy and Pharmacology | 2009年 / 64卷
关键词：
Statin; Simvastatin; Irinotecan; Cetuximab; Lovastatin;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：657 / 663
页数：6
相关论文
共 50 条
  • [31] First-line treatment of metastatic colorectal cancer with irinotecan, oxaliplatin and 5-fluorouracil/leucovorin (FOLFOXIRI): results of a phase II study with a simplified biweekly schedule
    Masi, G
    Allegrini, G
    Cupini, S
    Marcucci, L
    Cerri, E
    Brunetti, I
    Fontana, E
    Ricci, S
    Andreuccetti, M
    Falcone, A
    ANNALS OF ONCOLOGY, 2004, 15 (12) : 1766 - 1772
  • [32] Phase II study of irinotecan, leucovorin, 5-fluorouracil and tegafur/uracil for metastatic colorectal cancer
    Kono, T
    Ebisawa, Y
    Tomita, I
    Chisato, N
    Kamiya, K
    Asama, T
    Ayabe, T
    Ashida, T
    Kohgo, Y
    Kasai, S
    JOURNAL OF CHEMOTHERAPY, 2005, 17 (02) : 224 - 227
  • [33] Phase II Study of Biweekly Paclitaxel Plus Infusional 5-Fluorouracil and Leucovorin as First-Line Chemotherapy in Patients With Advanced Gastric Cancer
    Wang, Fenghua
    Wang, Zhiqiang
    Zhou, Ningning
    An, Xin
    Xu, Ruihua
    He, Youjian
    Li, Yuhong
    AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS, 2011, 34 (04): : 401 - 405
  • [34] Multicenter phase II study of infusional 5-fluorouracil (5-FU), leucovorin, and oxaliplatin, plus biweekly cetuximab as first-line treatment in patients with metastatic colorectal cancer (CELINE trial)
    Kotake, Masanori
    Aoyama, Toru
    Munemoto, Yoshinori
    Doden, Kenji
    Kataoka, Masato
    Kobayashi, Kenji
    Nishimura, Genichi
    Fujita, Hidehito
    Nakamura, Keishi
    Takehara, Akira
    Tanaka, Chihiro
    Sakamot, Junichi
    NagatA', Naoki
    Oba, Koji
    Kondo, Ken
    ONCOLOGY LETTERS, 2017, 13 (02) : 747 - 753
  • [35] Single-centre experience with third-line chemotherapy with irinotecan plus 5-fluorouracil and leucovorin (FOLFIRI) in metastatic gastric cancer patients
    Pasquini, G.
    Fornaro, L.
    Vasile, E.
    Lencioni, M.
    Petrini, I.
    Caparello, C.
    Vivaldi, C.
    Musettini, G.
    Falcone, A.
    ANNALS OF ONCOLOGY, 2015, 26 : 100 - 100
  • [36] Irinotecan plus folinic acid/continuous 5-fluorouracil as simplified bimonthly FOLFIRI regimen for first-line therapy of metastatic colorectal cancer
    Andreas Teufel
    Silke Steinmann
    Jürgen Siebler
    Christiane Zanke
    Herbert Hohl
    Bernd Adami
    M Schroeder
    O Klein
    Thomas Höhler
    Peter R Galle
    Michael Heike
    Markus Moehler
    BMC Cancer, 4
  • [37] A Phase II study of ANGIOZYME® in combination with 5-fluorouracil, leucovorin and irinotecan in the treatment of metastatic colorectal cancer patients
    Usman, N
    Venook, A
    Hurwitz, H
    Cunningham, C
    Fuchs, C
    Burris, H
    Schwartzberg, L
    Pelley, R
    Miller, WH
    Modiano, M
    EUROPEAN JOURNAL OF CANCER, 2002, 38 : S72 - S72
  • [38] Triplet combination with irinotecan plus oxaliplatin plus continuous-infusion fluorouracil and leucovorin as first-line treatment in metastatic colorectal cancer: A multicenter phase II trial
    Souglakos, J
    Mavroudis, D
    Kakolyris, S
    Kourousis, C
    Vardakis, N
    Androulakis, N
    Agelaki, S
    Kalbakis, K
    Tsetis, D
    Athanasiadis, N
    Samonis, G
    Georgoulias, V
    JOURNAL OF CLINICAL ONCOLOGY, 2002, 20 (11) : 2651 - 2657
  • [39] Phase II trial of oxaliplatin/irinotecan/5-fluorouracil/leucovorin for metastatic colorectal cancer
    McWilliams, Robert R.
    Goetz, Matthew P.
    Morlan, Bruce W.
    Salim, Muhammad
    Rowland, Kendrith M.
    Krook, James E.
    Ames, Matthew M.
    Erlichman, Charles
    CLINICAL COLORECTAL CANCER, 2007, 6 (07) : 516 - 521
  • [40] Phase I study of gefitinib, irinotecan, 5-fluorouracil and leucovorin in patients with metastatic colorectal cancer
    Jeffrey A. Meyerhardt
    Jeffrey W. Clark
    Jeffrey G. Supko
    Joseph P. Eder
    Shuji Ogino
    Clinton F. Stewart
    Ferdinando D’Amato
    Janet Dancey
    Peter C. Enzinger
    Andrew X. Zhu
    David P. Ryan
    Craig C. Earle
    Robert J. Mayer
    Ann Michelini
    Kate Kinsella
    Charles S. Fuchs
    Cancer Chemotherapy and Pharmacology, 2007, 60 : 661 - 670
12345