Development and validation of a simplified method to generate human microglia from pluripotent stem cells

被引：0
|
作者：
Amanda McQuade
Morgan Coburn
Christina H. Tu
Jonathan Hasselmann
Hayk Davtyan
Mathew Blurton-Jones
机构：
[1] University of California,Department of Neurobiology & Behavior
[2] University of California,Sue and Bill Gross Stem Cell Research Center
[3] University of California,Institute for Memory Impairments and Neurological Disorders
来源：
Molecular Neurodegeneration | / 13卷
关键词：
Microglia; Neurodegeneration; GWAS; Stem cells; iPSCs; Hematopoietic precursor cells; Phagocytosis; TGFB; IDE1; Differentiation;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [21] Functional microglia derived from human pluripotent stem cells empower retinal organs
    Mei-Ling Gao
    Xiao Zhang
    Fang Han
    Jia Xu
    Si-Jian Yu
    Kangxin Jin
    Zi-Bing Jin
    Science China(Life Sciences), 2022, 65 (06) : 1057 - 1071
  • [22] Functional microglia derived from human pluripotent stem cells empower retinal organ
    Gao, Mei-Ling
    Zhang, Xiao
    Han, Fang
    Xu, Jia
    Yu, Si-Jian
    Jin, Kangxin
    Jin, Zi-Bing
    SCIENCE CHINA-LIFE SCIENCES, 2022, 65 (06) : 1057 - 1071
  • [23] Hematopoietic Development from Human Induced Pluripotent Stem Cells
    Lengerke, Claudia
    Grauer, Matthias
    Niebuhr, Nina I.
    Riedt, Tamara
    Kanz, Lothar
    Park, In-Hyun
    Daley, George Q.
    HEMATOPOIETIC STEM CELLS VII, 2009, 1176 : 219 - +
  • [24] Development of Islet Organoids from Human Pluripotent Stem Cells
    Ye, K.
    Wang, W.
    Jin, S.
    TISSUE ENGINEERING PART A, 2015, 21 : S354 - S354
  • [25] Development and Validation of a GMP Process to Generate Retinal Pigment Epithelial Cells (RPE) Derived from Autologous Induced Pluripotent Stem Cells (iPSCs)
    Sarkar, Sarmila
    Thakkar, Aditi
    Hua, Fang
    Highfill, Steven
    Jha, Shekhar
    Bharti, Kapil
    Stroncek, David
    MOLECULAR THERAPY, 2019, 27 (04) : 292 - 292
  • [26] A rapid chemical reprogramming system to generate human pluripotent stem cells
    Wang, Yanglu
    Peng, Fangqi
    Yang, Zhihan
    Cheng, Lin
    Cao, Jingxiao
    Fu, Xiaodi
    He, Huanjing
    Cai, Ruyi
    Zeng, Weizhen
    Dong, Yingshuai
    Chen, Guanxian
    Peng, Gongxin
    Liuyang, Shijia
    Wang, Guan
    Wang, Jinlin
    Mu, Rong
    Li, Cheng
    Guan, Jingyang
    Deng, Hongkui
    NATURE CHEMICAL BIOLOGY, 2025,
  • [27] A novel efficient strategy to generate liver sinusoidal endothelial cells from human pluripotent stem cells
    Tian, Shang-Ping
    Ge, Jian-Yun
    Song, Yu-Mu
    Yu, Xiao-Qing
    Chen, Wen-Hao
    Chen, Yu-Ying
    Ye, Di
    Zheng, Yun-Wen
    SCIENTIFIC REPORTS, 2024, 14 (01):
  • [28] High-Fidelity Modeling of Human Microglia with Pluripotent Stem Cells
    Jiang, Peng
    Turkalj, Luka
    Xu, Ranjie
    CELL STEM CELL, 2020, 26 (05) : 629 - 631
  • [29] Generation of pure monocultures of human microglia-like cells from induced pluripotent stem cells
    Banerjee, Poulomi
    Paza, Evdokia
    Perkins, Emma M.
    James, Owen G.
    Kenkhuis, Boyd
    Lloyd, Amy F.
    Burr, Karen
    Story, David
    Yusuf, Dilmurat
    He, Xin
    Backofen, Rolf
    Dando, Owen
    Chandran, Siddharthan
    Priller, Josef
    STEM CELL RESEARCH, 2020, 49
  • [30] Establishment of a Method of Hepatocyte Differentiation from Human Pluripotent Stem Cells for Innovative Drug Development
    Takayama, Kazuo
    YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 2015, 135 (10): : 1141 - 1146
12345