PI3K inhibitor GDC-0941 enhances apoptotic effects of BH-3 mimetic ABT-737 in AML cells in the hypoxic bone marrow microenvironment

被引:0
|
作者
Linhua Jin
Yoko Tabe
Kensuke Kojima
Masato Shikami
Juliana Benito
Vivian Ruvolo
Rui-Yu Wang
Teresa McQueen
Stefan O. Ciurea
Takashi Miida
Michael Andreeff
Marina Konopleva
机构
[1] Juntendo University School of Medicine,Department of Clinical Laboratory Medicine
[2] The University of Texas MD Anderson Cancer Center,Department of Leukemia
[3] Aichi Medical University,Department of Hematology
[4] The University of Texas MD Anderson Cancer Center,Department of Stem Cell Transplantation and Cellular Therapy
来源
Journal of Molecular Medicine | 2013年 / 91卷
关键词
Acute myeloid leukemia; Bone marrow microenvironment; Hypoxia; Apoptosis; GDC-0941; ABT-737;
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学科分类号
摘要
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页码:1383 / 1397
页数:14
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