Cytotoxicity in vitro, cellular uptake, localization and apoptotic mechanism studies induced by ruthenium(II) complex

被引：0
|
作者：
Jincan Chen
Yao Zhang
Guodong Li
Fa Peng
Xinming Jie
Ji She
Guangzhi Dongye
Zhilin Zou
Shiwen Rong
Lanmei Chen
机构：
[1] Analysis Centre of Guangdong Medical University,Guangdong Key Laboratory for Research and Development of Nature Drugs
[2] Guangdong Medical University,Dongguan Key Laboratory of Drug Design and Formulation Technology, School of Pharmacy
[3] Guangdong Medical University,The First Clinical Medical College
[4] Guangdong Medical University,undefined
来源：
JBIC Journal of Biological Inorganic Chemistry | 2018年 / 23卷
关键词：
Ruthenium methylimidazole complex; Apoptosis; Mitochondrial dysfunction; ROS; DNA damage;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：261 / 275
页数：14
相关论文
共 50 条
  • [21] Mechanism of Cytotoxicity and Cellular Uptake of Lipophilic Inert Dinuclear Polypyridylruthenium(II) Complexes
    Pisani, Michelle J.
    Fromm, Phillip D.
    Mulyana, Yanyan
    Clarke, Ronald J.
    Koerner, Heinrich
    Heimann, Kirsten
    Collins, J. Grant
    Keene, F. Richard
    CHEMMEDCHEM, 2011, 6 (05) : 848 - 858
  • [22] In vitro cytotoxicity and cellular uptake of gold nanoparticles
    De Lapuente, J.
    Ramos, D.
    Porredon, C.
    Di Guglielmo, C.
    Borras, M.
    TOXICOLOGY LETTERS, 2010, 196 : S284 - S284
  • [23] Cytotoxicity, cellular uptake, and subcellular localization of a nitrogen oxide and aminopropyl-β-lactose derivative ruthenium complex used as nitric oxide delivery agent
    dos Santos, Joicy Santamalvina
    Ramos, Loyanne C.
    Ferreira, Lucimara P.
    Campo, Vanessa Leira
    de Rezende, Lucas C. D.
    Emery, Flavio da Silva
    da Silva, Roberto Santana
    NITRIC OXIDE-BIOLOGY AND CHEMISTRY, 2019, 86 : 38 - 47
  • [24] Cytotoxicity, cellular uptake, cell cycle arrest, apoptosis, reactive oxygen species and DNA-binding studies of ruthenium(II) complexes
    Yang-Yin Xie
    Gan-Jian Lin
    Guang-Bin Jiang
    Zhen-Hua Liang
    Hong-Liang Huang
    Yun-Jun Liu
    Transition Metal Chemistry, 2013, 38 : 563 - 571
  • [25] Cytotoxicity, cellular uptake, cell cycle arrest, apoptosis, reactive oxygen species and DNA-binding studies of ruthenium(II) complexes
    Xie, Yang-Yin
    Lin, Gan-Jian
    Jiang, Guang-Bin
    Liang, Zhen-Hua
    Huang, Hong-Liang
    Liu, Yun-Jun
    TRANSITION METAL CHEMISTRY, 2013, 38 (05) : 563 - 571
  • [26] Cytotoxicity, cellular uptake, and DNA interactions of new monodentate ruthenium(II) complexes containing terphenyl arenes
    Bugarcic, Tijana
    Novakova, Olga
    Halamikova, Anna
    Zerzankova, Lenka
    Vrana, Oldrich
    Kasparkova, Jana
    Habtemariam, Abraha
    Parsons, Simon
    Sadler, Peter J.
    Brabec, Viktor
    JOURNAL OF MEDICINAL CHEMISTRY, 2008, 51 (17) : 5310 - 5319
  • [27] Comparative Studies of the Cellular Uptake, Subcellular Localization, and Cytotoxic and Phototoxic Antitumor Properties of Ruthenium(II)-Porphyrin Conjugates with Different Linkers
    Zhang, Jing-Xiang
    Zhou, Jun-Wei
    Chan, Chi-Fai
    Lau, Terrence Chi-Kong
    Kwong, Daniel W. J.
    Tam, Hoi-Lam
    Mak, Nai-Ki
    Wong, Ka-Leung
    Wong, Wai-Kwok
    BIOCONJUGATE CHEMISTRY, 2012, 23 (08) : 1623 - 1638
  • [28] Cytotoxicity In Vitro, Apoptosis, Cellular Uptake, Cell Cycle Distribution, Mitochondrial Membrane Potential Detection, DNA Binding, and Photocleavage of Ruthenium(II) Complexes
    Lin, Gan-Jian
    Li, Zheng-Zheng
    Yao, Jun-Hua
    Huang, Hong-Liang
    Xie, Yang-Yin
    Liu, Yun-Jun
    AUSTRALIAN JOURNAL OF CHEMISTRY, 2013, 66 (05) : 555 - 563
  • [29] In vitro cytotoxicity and antibacterial studies of ruthenium(II) DMSO complexes with S-allyldithiocarbazate
    Ponnusamy, Selvakumar
    Ramasamy, Narayanasamy
    INTERNATIONAL JOURNAL OF MATERIALS & PRODUCT TECHNOLOGY, 2017, 55 (1-3): : 142 - 155
  • [30] In vitro susceptibility and cellular uptake for a new class of antimicrobial agents: dinuclear ruthenium(II) complexes
    Li, Fangfei
    Feterl, Marshall
    Mulyana, Yanyan
    Warner, Jeffrey M.
    Collins, J. Grant
    Keene, F. Richard
    JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2012, 67 (11) : 2686 - 2695
12345