Condensation of 1-substituted 1,2,3,9a-tetrahydro-9H-imidazo[1,2-a]-indol-2-one derivatives with aromatic aldehydes

被引：0

作者：

Sackus A. ^{[1
]}

Amankaviciene V. ^{[1
]}

机构：

[1] Department of Organic Chemistry, Faculty of Chemical Technology, Kaunas University of Technology

来源：

Chemistry of Heterocyclic Compounds | 2002年 / 38卷 / 07期

关键词：

1,2,3,9a-tetrahydro-9H-imidazo[1,2-a]indol-2-one; 9a-(2-phenylethenyl)-1,2,3,9a-tetrahydro-9H-imidazo[1,2-a]indol-2-one; Alkylation; Condensation;

D O I：

10.1023/A:1020685704961

中图分类号：

学科分类号：

摘要：

Condensation of 1-alkyl-, 1-allyl-, and 1-benzyl-1,2,3,9a-tetrahydro-9H-imidazo[1,2-a]indol-2-ones with benzaldehydes in acetic acid and subsequent treatment of the reaction mixture with potassium hydroxide afforded 1-substituted 9a-(2-phenylethenyl)-1,2,3,9a-tetrahydro-9H-imidazo[1,2-a]indol-2-one derivatives. 1-Methyl- and 1-ethyl-9a-[2-(4-dimethylaminophenyl)ethenyl]-1,2,3,9a-tetrahydro-9H-imidazo [1,2-a]indol-2-ones were synthesized by alkylation of 9a-[2-(4-dimethylaminophenyl)ethenyl]-1,2,3,9a-tetrahydro-9H-imidazo[1,2-a] indol-2-one with methyl- and ethyl iodides in DMF in the presence of a strong base.

引用

页码：822 / 827

页数：5

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