Antimicrobial activity of quaternary ammonium salts: structure-activity relationship

被引：0
|
作者：
Mallikarjuna N. Nadagouda
Pooja Vijayasarathy
Aebin Sin
Heeyeon Nam
Sanaullah Khan
Javad B. M. Parambath
Ahmed A. Mohamed
Changseok Han
机构：
[1] Wright State University,Department of Mechanical and Materials Engineering
[2] University of Kentucky,Materials Science and Engineering
[3] Graduate School of INHA University,Program in Environmental & Polymer Engineering
[4] Women University,Department of Chemistry
[5] University of Sharjah,Department of Chemistry, College of Sciences
[6] INHA University,Department of Environmental Engineering
来源：
Medicinal Chemistry Research | 2022年 / 31卷
关键词：
Antibacterial activities; Disinfectants; Quaternary ammonium salts; Biofilms;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Compounds with antimicrobial activity have gained much attention in research due to the outbreak of coronavirus disease 2019 (COVID-19). Quaternary ammonium salts (QASs) are an emerging group of antibacterial agents that are used as disinfectants. Many studies have been carried out involving the applications of QASs as antifouling agents for the inhibition of biofilm growth on medical implants and antibacterials on surfaces and in an aquatic environment. In investigating the antibacterial activity of QASs, we addressed the structure-activity relationship and the physicochemical factors. This review is focused on the fine-tuning of the chemical structures of QASs for their applications as wide antibacterial agents.
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页码：1663 / 1678
页数：15
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