Genomics-driven discovery of the pneumocandin biosynthetic gene cluster in the fungus Glarea lozoyensis

被引:0
|
作者
Li Chen
Qun Yue
Xinyu Zhang
Meichun Xiang
Chengshu Wang
Shaojie Li
Yongsheng Che
Francisco Javier Ortiz-López
Gerald F Bills
Xingzhong Liu
Zhiqiang An
机构
[1] State Key Laboratory of Mycology,Key Laboratory of Insect Developmental and Evolutionary Biology, Institute of Plant physiology and Ecology, Shanghai Institutes for Biological Sciences
[2] Institute of Microbiology,Texas Therapeutics Institute, the Brown Foundation Institute of Molecular Medicine
[3] Chinese Academy of Sciences,undefined
[4] University of Chinese Academy of Sciences,undefined
[5] Chinese Academy of Sciences,undefined
[6] Beijing Institute of Pharmacology & Toxicology,undefined
[7] Fundación MEDINA,undefined
[8] Centro de Excelencia en Investigación de Medicamentos Innovadores en Andalucía,undefined
[9] University of Texas Health Science Center at Houston,undefined
来源
BMC Genomics | / 14卷
关键词
Polyketide; Cyclic Hexapeptide; Orsellinic Acid; Tolypocladium Inflatum; Dimethylallyl Tryptophan;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [41] The sirodesmin biosynthetic gene cluster of the plant pathogenic fungus Leptosphaeria maculans
    Gardiner, DM
    Cozijnsen, AJ
    Wilson, LM
    Pedras, MSC
    Howlett, BJ
    MOLECULAR MICROBIOLOGY, 2004, 53 (05) : 1307 - 1318
  • [42] Discovery of a Potential Liver Fibrosis Inhibitor from a Mushroom Endophytic Fungus by Genome Mining of a Silent Biosynthetic Gene Cluster
    Cheng, Jin-Tao
    Wang, Han-Min
    Yu, Jia-Hui
    Sun, Chen-Fan
    Cao, Fei
    Jiang, Xin-Hang
    Chen, Xin-Ai
    Zhao, Qing-Wei
    Gan, Li-She
    Xie, Rong-Rong
    Wang, Shi-Lei
    Li, Jia
    Zang, Yi
    Mao, Xu-Ming
    JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2021, 69 (38) : 11303 - 11310
  • [43] Genomics-Driven Discovery of Benzoxazole Alkaloids from the Marine-Derived Micromonospora sp. SCSIO 07395
    Cheng, Ziqian
    Zhang, Qingbo
    Peng, Jing
    Zhao, Xiaoyang
    Ma, Liang
    Zhang, Changsheng
    Zhu, Yiguang
    MOLECULES, 2023, 28 (02):
  • [44] A Genomics Based Discovery of Secondary Metabolite Biosynthetic Gene Clusters in Aspergillus ustus
    Pi, Borui
    Yu, Dongliang
    Dai, Fangwei
    Song, Xiaoming
    Zhu, Congyi
    Li, Hongye
    Yu, Yunsong
    PLOS ONE, 2015, 10 (02):
  • [45] Identification of a Novel Biosynthetic Gene Cluster in Aspergillus niger Using Comparative Genomics
    Evdokias, Gregory
    Semper, Cameron
    Mora-Ochomogo, Montserrat
    Di Falco, Marcos
    Nguyen, Thi Truc Minh
    Savchenko, Alexei
    Tsang, Adrian
    Benoit-Gelber, Isabelle
    JOURNAL OF FUNGI, 2021, 7 (05)
  • [46] Microfluidic automated plasmid library enrichment for biosynthetic gene cluster discovery
    Xu, Peng
    Modavi, Cyrus
    Demaree, Benjamin
    Twigg, Frederick
    Liang, Benjamin
    Sun, Chen
    Zhang, Wenjun
    Abate, Adam R.
    NUCLEIC ACIDS RESEARCH, 2020, 48 (08)
  • [47] Discovery of the Tyrobetaine Natural Products and Their Biosynthetic Gene Cluster via Metabologenomics
    Parkinson, Elizabeth I.
    Tryon, James H.
    Goering, Anthony W.
    Ju, Kou-San
    McClure, Ryan A.
    Kemball, Jeremy D.
    Zhukovsky, Sara
    Labeda, David P.
    Thomson, Regan J.
    Kelleher, Neil L.
    Metcalf, William W.
    ACS CHEMICAL BIOLOGY, 2018, 13 (04) : 1029 - 1037
  • [48] The Integration of Genome Mining, Comparative Genomics, and Functional Genetics for Biosynthetic Gene Cluster Identification
    Williams, Ashley N.
    Sorout, Naveen
    Cameron, Alexander J.
    Stavrinides, John
    FRONTIERS IN GENETICS, 2020, 11
  • [49] Genomics-Driven Discovery of a Novel Glutarimide Antibiotic from Burkholderia gladioli Reveals an Unusual Polyketide Synthase Chain Release Mechanism
    Nakou, Ioanna T.
    Jenner, Matthew
    Dashti, Yousef
    Romero-Canelón, Isolda
    Masschelein, Joleen
    Mahenthiralingam, Eshwar
    Challis, Gregory L.
    Advanced Materials, 2020, 132 (51) : 23345 - 23353
  • [50] Genomics-Driven Discovery of a Novel Glutarimide Antibiotic from Burkholderia gladioli Reveals an Unusual Polyketide Synthase Chain Release Mechanism
    Nakou, Ioanna T.
    Jenner, Matthew
    Dashti, Yousef
    Romero-Canelon, Isolda
    Masschelein, Joleen
    Mahenthiralingam, Eshwar
    Challis, Gregory L.
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2020, 59 (51) : 23145 - 23153