Clinical development of trastuzumab in breast cancer

被引：4

作者：

Tokuda Y. ^{[1
]}

Ohta M. ^{[1
]}

Suzuki Y. ^{[1
]}

Kubota M. ^{[1
]}

Tajima T. ^{[1
]}

机构：

[1] Department of Surgery, Tokai University School of Medicine

来源：

Breast Cancer | 2001年 / 8卷 / 2期

关键词：

Breast cancer; HER2/neu; Humanized monoclonal antibody; Trastuzumab;

D O I：

10.1007/BF02967486

中图分类号：

学科分类号：

摘要：

The HER-2/neu protein is thought to be a unique and useful target for antibody therapy of cancers overexpressing the HER-2/neu gene. The recombinant humanized anti-HER-2 monoclonal antibody, trastuzumab (Herceptin ™) is now available for clinical use in the U.S.A. It is also expected to be available in Japan in the near future. In this paper, the details of this novel biologic agent are reviewed in conjunction with a phase I study performed in Japan.

引用

页码：93 / 97

页数：4

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