Factors Affecting the Clinical Development of Cytochrome P450 3A Substrates

被引：0
|
作者：
Megan A. Gibbs
Natilie A. Hosea
机构：
[1] Pfizer Inc.,Clinical Pharmacokinetics and Pharmacodynamics
[2] Pfizer Inc.,Pharmacokinetics, Dynamics and Metabolism
来源：
Clinical Pharmacokinetics | 2003年 / 42卷
关键词：
Midazolam; Ketoconazole; Felodipine; Terfenadine; Grapefruit Juice;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The objective of this review is to evaluate the risks associated with the discovery and development of cytochrome P450 (CYP) 3A substrates.
引用
收藏
页码：969 / 984
页数：15
相关论文
共 50 条
  • [1] Factors affecting the clinical development of cytochrome P450 3A substrates
    Gibbs, MA
    Hosea, NA
    CLINICAL PHARMACOKINETICS, 2003, 42 (11) : 969 - 984
  • [2] Risperidone and cytochrome P450 3A
    deLeon, J
    Bork, J
    JOURNAL OF CLINICAL PSYCHIATRY, 1997, 58 (10) : 450 - 450
  • [3] Cytochrome P450 3A and their regulation
    Burk, O
    Wojnowski, L
    NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 2004, 369 (01) : 105 - 124
  • [4] Cytochrome P450 3A and their regulation
    Oliver Burk
    Leszek Wojnowski
    Naunyn-Schmiedeberg's Archives of Pharmacology, 2004, 369 : 105 - 124
  • [5] The influence of age and sex on the clearance of cytochrome P450 3A substrates
    Cotreau, MM
    von Moltke, LL
    Greenblatt, DJ
    CLINICAL PHARMACOKINETICS, 2005, 44 (01) : 33 - 60
  • [6] The Influence of Age and Sex on the Clearance of Cytochrome P450 3A Substrates
    Monette M. Cotreau
    Lisa L. von Moltke
    David J. Greenblatt
    Clinical Pharmacokinetics, 2005, 44 : 33 - 60
  • [7] Pharmacokinetic Interactions of Rolapitant With Cytochrome P450 3A Substrates in Healthy Subjects
    Wang, Xiaodong
    Wang, Jing
    Arora, Sujata
    Hughes, Lorraine
    Christensen, Jennifer
    Lu, Sharon
    Zhang, Zhi-Yi
    JOURNAL OF CLINICAL PHARMACOLOGY, 2019, 59 (04): : 488 - 499
  • [8] Factors affecting cytochrome P-450 3A activity in cancer patients
    Baker, SD
    van Schaik, RHN
    Rivory, LP
    ten Tije, AJ
    Dinh, K
    Graveland, WJ
    Schenk, PW
    Charles, KA
    Clarke, SJ
    Carducci, MA
    McGuire, WP
    Dawkins, F
    Gelderblom, H
    Verweij, J
    Sparreboom, A
    CLINICAL CANCER RESEARCH, 2004, 10 (24) : 8341 - 8350
  • [9] Posttranscriptional elevation of cytochrome p450 3A expression
    Zangar, RC
    Hernandez, M
    Novak, RF
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1997, 231 (01) : 203 - 205
  • [10] Cytochrome P450 3A - Ontogeny and drug disposition
    de Wildt, SN
    Kearns, GL
    Leeder, JS
    van den Anker, JN
    CLINICAL PHARMACOKINETICS, 1999, 37 (06) : 485 - 505
12345