Key words Inflammatory;
myopathies;
Autoimmunity;
Muscle;
Collagen vascular diseases;
Malignancies;
D O I:
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摘要:
The inflammatory myopathies are a heterogeneous group of muscle diseases characterized by muscle degeneration mediated by inflammatory processes. They may be idiopathic, as in polymyositis, dermatomyositis and inclusion body myositis, or associated with systemic disorders such as malignancies, overlap syndromes, and retroviral infection. The pathogenesis of each disease is discussed together with more recent molecular and cellular immunology findings. Salient diagnostic, clinical and pharmacological features are also reviewed.
机构:
George Washington Univ, Childrens Natl Med Ctr, Med Genet Res Ctr, Washington, DC 20010 USA
George Washington Univ, Inst Biomed Sci, Washington, DC 20010 USAGeorge Washington Univ, Childrens Natl Med Ctr, Med Genet Res Ctr, Washington, DC 20010 USA
Coley, William
Nagaraju, Kanneboyina
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George Washington Univ, Childrens Natl Med Ctr, Med Genet Res Ctr, Washington, DC 20010 USA
George Washington Univ, Inst Biomed Sci, Washington, DC 20010 USAGeorge Washington Univ, Childrens Natl Med Ctr, Med Genet Res Ctr, Washington, DC 20010 USA
机构:
Fiona Stanley Hosp, Neurol Dept, 11 Robin Warren Dr, Murdoch, WA 6150, AustraliaFiona Stanley Hosp, Neurol Dept, 11 Robin Warren Dr, Murdoch, WA 6150, Australia
Ashton, Catherine
Paramalingam, Shereen
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机构:
Fiona Stanley Hosp, Dept Rheumatol, Murdoch, WA, Australia
Univ Notre Dame, Fremantle, WA, AustraliaFiona Stanley Hosp, Neurol Dept, 11 Robin Warren Dr, Murdoch, WA 6150, Australia
Paramalingam, Shereen
Stevenson, Brittany
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Fiona Stanley Hosp, Immunol Dept, Murdoch, WA, Australia
Sir Charles Gairdner Hosp, PathWest, Immunol Dept, Perth, WA, AustraliaFiona Stanley Hosp, Neurol Dept, 11 Robin Warren Dr, Murdoch, WA 6150, Australia
Stevenson, Brittany
Brusch, Anna
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Sir Charles Gairdner Hosp, PathWest, Dept Clin Immunol, Perth, WA, AustraliaFiona Stanley Hosp, Neurol Dept, 11 Robin Warren Dr, Murdoch, WA 6150, Australia
Brusch, Anna
Needham, Merrilee
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机构:
Fiona Stanley Hosp, Neurol Dept, 11 Robin Warren Dr, Murdoch, WA 6150, Australia
Murdoch Univ, Inst Immunol & Infect Dis, Perth, WA, Australia
Perron Inst Neurol & Translat Sci, Perth, WA, Australia
Univ Notre Dame, Fremantle, WA, AustraliaFiona Stanley Hosp, Neurol Dept, 11 Robin Warren Dr, Murdoch, WA 6150, Australia
机构:
Bordeaux Univ Hosp, Dept Pathol, Pl Amelie Raba Leon, F-33076 Bordeaux, FranceBordeaux Univ Hosp, Dept Pathol, Pl Amelie Raba Leon, F-33076 Bordeaux, France
Lepreux, Sebastien
Hainfellner, Johannes A.
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Med Univ Vienna, Inst Neurol & Comprehens Canc Ctr, CNS Unit, Vienna, AustriaBordeaux Univ Hosp, Dept Pathol, Pl Amelie Raba Leon, F-33076 Bordeaux, France
Hainfellner, Johannes A.
Vital, Anne
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Bordeaux Univ Hosp, Dept Pathol, Pl Amelie Raba Leon, F-33076 Bordeaux, France
Univ Bordeaux, Inst Malad Neurodegenerat, UMR 5293, Bordeaux, FranceBordeaux Univ Hosp, Dept Pathol, Pl Amelie Raba Leon, F-33076 Bordeaux, France
机构:
Univ Western Ontario, Schulich Sch Med & Dent, St Josephs Hlth Care, Div Rheumatol, London, ON N6A 4V2, CanadaUniv Western Ontario, Schulich Sch Med & Dent, St Josephs Hlth Care, Div Rheumatol, London, ON N6A 4V2, Canada
Boyd, Tristan
Kavanaugh, Arthur
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Univ Calif San Diego, Sch Med, Div Rheumatol Allergy & Immunol, La Jolla, CA 92093 USAUniv Western Ontario, Schulich Sch Med & Dent, St Josephs Hlth Care, Div Rheumatol, London, ON N6A 4V2, Canada