Immunomodulatory activity of SGI-110, a 5-aza-2′-deoxycytidine-containing demethylating dinucleotide

被引:0
|
作者
Sandra Coral
Giulia Parisi
Hugues J. M. G. Nicolay
Francesca Colizzi
Riccardo Danielli
Elisabetta Fratta
Alessia Covre
Pietro Taverna
Luca Sigalotti
Michele Maio
机构
[1] Centro di Riferimento Oncologico,Cancer Bioimmunotherapy Unit
[2] Istituto Toscano Tumori,Division of Medical Oncology and Immunotherapy, Department of Oncology, University Hospital of Siena
[3] Astex Pharmaceuticals,undefined
[4] Inc.,undefined
来源
关键词
DNA hypomethylating agent; Cancer; Immunotherapy; Epigenetics;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:605 / 614
页数:9
相关论文
共 50 条
  • [21] KINETICS OF PHOSPHORYLATION OF 5-AZA-2'-DEOXYCYTIDINE BY DEOXYCYTIDINE KINASE
    MOMPARLER, RL
    DERSE, D
    BIOCHEMICAL PHARMACOLOGY, 1979, 28 (08) : 1443 - 1444
  • [22] Pharmacology of 5-Aza-2′-deoxycytidine (decitabine)
    Momparler, RL
    SEMINARS IN HEMATOLOGY, 2005, 42 (03) : S9 - S16
  • [23] AN ANALYTICAL STUDY OF 5-AZA-2'-DEOXYCYTIDINE
    TOMANKOVA, H
    ZYKA, J
    PILECKOVA, Z
    MICROCHEMICAL JOURNAL, 1984, 29 (03) : 333 - 340
  • [24] Analysis of genes upregulated by the demethylating agent 5-aza-2′-deoxycytidine in gastric cancer cell lines
    Mikata, Rintaro
    Yokosuka, Osamu
    Fukai, Kenichi
    Imazeki, Fumio
    Arai, Makoto
    Tada, Motohisa
    Kurihara, Tomoko
    Zhang, Kaiyu
    Kanda, Tatsuo
    Saisho, Hiromitsu
    INTERNATIONAL JOURNAL OF CANCER, 2006, 119 (07) : 1616 - 1622
  • [25] 5-aza-2′-deoxycytidine in myelodysplasia.
    Kell, WJ
    Burnett, AK
    BRITISH JOURNAL OF HAEMATOLOGY, 1998, 101 : 64 - 64
  • [26] Antileukemia activity of the combination of 5-aza-2′-deoxycytidine with valproic acid
    Yang, H
    Hoshino, K
    Sanchez-Gonzalez, B
    Kantarjian, H
    Garcia-Manero, G
    LEUKEMIA RESEARCH, 2005, 29 (07) : 739 - 748
  • [27] POTENTIATION OF MYOD1 ACTIVITY BY 5-AZA-2'-DEOXYCYTIDINE
    CHEN, J
    JONES, PA
    CELL GROWTH & DIFFERENTIATION, 1990, 1 (08): : 383 - 392
  • [28] Prevention of gastric cancers induced by Helicobacter pylori infection with a DNA demethylating reagent, 5-aza-2′-deoxycytidine
    Niwa, Tohru
    Toyoda, Takeshi
    Tsukamoto, Tetsuya
    Mori, Akiko
    Tatematsu, Masae
    Ushijima, Toshikazu
    CANCER RESEARCH, 2011, 71
  • [29] Pharmacodynamic effects in patients treated with 6 hour infusion of the demethylating agent 5-aza-2′deoxycytidine (decitabine).
    Brown, R
    Appleton, K
    Plumb, JA
    McCormick, C
    Lee, C
    Barrett, S
    Tang, A
    Schaetzlein, A
    Kaye, SB
    Judson, I
    McKay, HJ
    CLINICAL CANCER RESEARCH, 2005, 11 (24) : 9071S - 9072S
  • [30] Delineating the effect of demethylating agent 5-aza-2′deoxycytidine on human Caco-2 colonic carcinoma cells
    Li, Xiumei
    Qin, Bingzhao
    Liu, Bo
    ONCOLOGY LETTERS, 2016, 12 (01) : 139 - 143