Immunomodulatory activity of SGI-110, a 5-aza-2′-deoxycytidine-containing demethylating dinucleotide

被引:0
|
作者
Sandra Coral
Giulia Parisi
Hugues J. M. G. Nicolay
Francesca Colizzi
Riccardo Danielli
Elisabetta Fratta
Alessia Covre
Pietro Taverna
Luca Sigalotti
Michele Maio
机构
[1] Centro di Riferimento Oncologico,Cancer Bioimmunotherapy Unit
[2] Istituto Toscano Tumori,Division of Medical Oncology and Immunotherapy, Department of Oncology, University Hospital of Siena
[3] Astex Pharmaceuticals,undefined
[4] Inc.,undefined
来源
关键词
DNA hypomethylating agent; Cancer; Immunotherapy; Epigenetics;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:605 / 614
页数:9
相关论文
共 50 条
  • [1] Immunomodulatory activity of SGI-110, a 5-aza-2′-deoxycytidine-containing demethylating dinucleotide
    Coral, S.
    Sigalotti, L.
    Parisi, G.
    Colizzi, F.
    Fratta, E.
    Nicolay, H. J. M.
    Taverna, P.
    Maio, M.
    EJC SUPPLEMENTS, 2010, 8 (07): : 173 - 174
  • [2] Immunomodulatory activity of SGI-110, a 5-aza-2′-deoxycytidine-containing demethylating dinucleotide
    Coral, Sandra
    Parisi, Giulia
    Nicolay, Hugues J. M. G.
    Colizzi, Francesca
    Danielli, Riccardo
    Fratta, Elisabetta
    Covre, Alessia
    Taverna, Pietro
    Sigalotti, Luca
    Maio, Michele
    CANCER IMMUNOLOGY IMMUNOTHERAPY, 2013, 62 (03) : 605 - 614
  • [3] Immunobiologic Activity of the Demethylating Dinucleotide SGI-110
    Coral, Sandra
    Sigalotti, Luca
    Fonsatti, Ester
    Parisi, Giulia
    Colizzi, Francesca
    Nicolay, Hugues J.
    Taverna, Pietro
    Maio, Michele
    JOURNAL OF IMMUNOTHERAPY, 2010, 33 (08) : 893 - 894
  • [4] S110, a 5-Aza-2′-Deoxycytidine-Containing Dinucleotide, Is an Effective DNA Methylation Inhibitor In vivo and Can Reduce Tumor Growth
    Chuang, Jody C.
    Warner, Steven L.
    Vollmer, David
    Vankayalapati, Hariprasad
    Redkar, Sanjeev
    Bearss, David J.
    Qiu, Xiangning
    Yoo, Christine B.
    Jones, Peter A.
    MOLECULAR CANCER THERAPEUTICS, 2010, 9 (05) : 1443 - 1450
  • [5] DNA demethylating therapy in MDS:: The experience with 5-AZA-2′-deoxycytidine (decitabine).
    Wijermans, P
    Luebbert, M
    Verhoef, G
    Bosly, A
    Ravoet, C
    Andre, M
    Ferrant, A
    Haak, H
    BLOOD, 1999, 94 (10) : 306A - 306A
  • [6] IMMUNOMODULATORY ACTIVITY OF SGI-110, A SECOND GENERATION HYPOMETHYLATING AGENT
    Maio, M.
    Choy, G.
    Covre, A.
    Parisi, G.
    Nicolay, H.
    Fratta, E.
    Fonsatti, E.
    Sigalotti, L.
    Coral, S.
    Taverna, P.
    Azab, M.
    ANNALS OF ONCOLOGY, 2013, 24 : 8 - 9
  • [7] 5-AZA-2′-deoxycytidine (5-AZA-CdR):: a demethylating agent affecting development and reproductive capacity
    Cisneros, FJ
    Branch, S
    JOURNAL OF APPLIED TOXICOLOGY, 2003, 23 (02) : 115 - 120
  • [8] Teratogenic effects of the demethylating agent 5-aza-2'-deoxycytidine in the Swiss Webster mouse
    Branch, S
    Francis, BM
    Brownie, CF
    Chernoff, N
    TOXICOLOGY, 1996, 112 (01) : 37 - 43
  • [9] 5-aza-2′-deoxycytidine, a DNA demethylating agent, inhibits metastatic melanoma invasiveness
    Etievant, Chantal
    Desjobert, Cecile
    Carrier, Arnaud
    Delmas, Audrey
    Tost, Jorg
    Favre, Gilles
    Riond, Joelle
    Arimondo, Paola
    CANCER RESEARCH, 2014, 74 (19)
  • [10] Induction of MAGE genes in lymphoid cells by the demethylating agent 5-aza-2'-deoxycytidine
    Shichijo, S
    Yamada, A
    Sagawa, K
    Iwamoto, O
    Sakata, M
    Nagai, K
    Itoh, K
    JAPANESE JOURNAL OF CANCER RESEARCH, 1996, 87 (07): : 751 - 756