Assessing disease activity and disease activity indices for inflammatory bowel disease.
被引:12
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作者:
Xiao Li F.
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机构:
Department of Community Health Sciences, University of Calgary, 3330 Hospital Drive NW, Canada T2N 4N1., Calgary, ABDepartment of Community Health Sciences, University of Calgary, 3330 Hospital Drive NW, Canada T2N 4N1., Calgary, AB
Xiao Li F.
[1
]
Sutherland L.R.
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机构:
Department of Community Health Sciences, University of Calgary, 3330 Hospital Drive NW, Canada T2N 4N1., Calgary, ABDepartment of Community Health Sciences, University of Calgary, 3330 Hospital Drive NW, Canada T2N 4N1., Calgary, AB
Sutherland L.R.
[1
]
机构:
[1] Department of Community Health Sciences, University of Calgary, 3330 Hospital Drive NW, Canada T2N 4N1., Calgary, AB
A crucial step in the development of clinical trials to determine the efficacy of various therapies for inflammatory bowel disease (IBD) has been the creation of activity indices. This article reviews the major components and operating characteristics of clinical activity indices commonly used in randomized, controlled trials of IBD therapy. In addition, the paper provides a brief overview of the developmental requirements for any new index.
机构:
University of Pittsburgh School of Medicine, Children's Hospital of Pittsburgh, One Children's Place, Pediatric Gastroenterology, PittsburghUniversity of Pittsburgh School of Medicine, Children's Hospital of Pittsburgh, One Children's Place, Pediatric Gastroenterology, Pittsburgh
机构:
Professor of Rheumatology, University of Oxford, Nuffield Orthopaedic Centre, Windmill Road, Oxford OX3 7LD, HeadingtonProfessor of Rheumatology, University of Oxford, Nuffield Orthopaedic Centre, Windmill Road, Oxford OX3 7LD, Headington