Pulsed Dendritic Cells for the Therapy of Experimental Glioma

被引：0
|
作者：
I. V. Chekhonin
O. I. Gurina
S. A. Cherepanov
M. A. Abakumov
K. P. Ionova
D. K. Zhigarev
A. V. Makarov
V. P. Chekhonin
机构：
[1] Ministry of Health of the Russian Federation,V. P. Serbsky Federal Medical Research Centre of Psychiatry and Narcology
[2] N. I. Pirogov Russian National Research Medical University,Department of Medical Nanobiotechnologies, Medical Biological Faculty
[3] Ministry of Health of the Russian Federation,undefined
来源：
Bulletin of Experimental Biology and Medicine | 2016年 / 161卷
关键词：
dendritic cells; glioma; neurospecific proteins; angiogenesis; periglioma zone;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
We obtained the morphologically, cytofluorometrically, and functionally mature dendritic cells from rats that were pulsed with antigens of the C6 glioma tissue extract. The concentrations of angiogenesis antigens (VEGF, VEGFR-1, and VEGFR-2) and periglioma zone proteins (GFAP, connexin 43, and BSAT1) in the pulsing extract were measured by ELISA. Our results drove us to a conclusion that despite mature phenotype of pulsed dendritic cell, the antigenic composition of glioma tissue extracts should be modified.
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页码：792 / 796
页数：4
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