Cardiovascular Effects of High-Molecular-Weight Compounds of Humic Nature

被引：0
|
作者：
M. V. Zykova
M. V. Belousov
T. V. Lasukova
A. S. Gorbunov
L. A. Logvinova
A. M. Dygai
机构：
[1] Ministry of Health of the Russian Federation,Siberian State Medical University
[2] Ministry of Science and Education,Tomsk State Pedagogical University
[3] Research Institute of Cardiology,E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center
[4] Russian Academy of Sciences,undefined
来源：
Bulletin of Experimental Biology and Medicine | 2017年 / 163卷
关键词：
humic acids; peat; heart; cardiovascular effects;
D O I：
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中图分类号：
学科分类号：
摘要：
The active ingredient extracted from the peat humic substances was characterized by physicochemical parameters evaluated by UV- and IR-spectroscopy, titration, and elemental (C, H, N) analysis. The cardiovascular effects of this ingredient were examined on isolated Langendorff-perfused rat heart. It was found that the active substance in a concentration range of 0.01-0.1 mg/ml produced a vasodilating effect; in addition, it decreased the end-diastolic and left-ventricular developed pressures.
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页码：206 / 209
页数：3
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