Stress ulcer prophylaxis with a proton pump inhibitor versus placebo in critically ill patients (SUP-ICU trial): study protocol for a randomised controlled trial

被引:0
|
作者
Mette Krag
Anders Perner
Jørn Wetterslev
Matt P. Wise
Mark Borthwick
Stepani Bendel
Paolo Pelosi
Frederik Keus
Anne Berit Guttormsen
Joerg C. Schefold
Morten Hylander Møller
机构
[1] Copenhagen University Hospital,Department of Intensive Care 4131
[2] Rigshospitalet,Department of Intensive Care 4131 and Centre for Research in Intensive Care (CRIC)
[3] Copenhagen University Hospital,Copenhagen Trial Unit, Centre for Clinical Intervention Research
[4] Rigshospitalet,Department of Adult Critical Care
[5] Copenhagen University Hospital,Pharmacy Department
[6] Rigshospitalet,Department of Intensive Care Medicine
[7] University Hospital of Wales,Department of Surgical Sciences and Integrated Diagnostics, IRCCS AOU San Martino IST
[8] Oxford University Hospitals NHS Trust,University of Groningen, Department of Critical Care
[9] Kuopio University Hospital,Department of Anaesthesia and Intensive Care
[10] University of Genoa,Department of Intensive Care Medicine
[11] University Medical Center Groningen,undefined
[12] Haukeland University Hospital and Clinical Institute 1 UiB,undefined
[13] University Hospital Inselspital,undefined
来源
Trials | / 17卷
关键词
Stress ulcer prophylaxis; Gastrointestinal bleeding; Intensive care unit; Critically ill; Randomised clinical trial; Placebo; Adverse event;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [21] GASTRIC COLONIZATION AND PNEUMONIA IN INTUBATED CRITICALLY ILL PATIENTS RECEIVING STRESS-ULCER PROPHYLAXIS - A RANDOMIZED, CONTROLLED TRIAL
    APTE, NM
    KARNAD, DR
    MEDHEKAR, TP
    TILVE, GH
    MORYE, S
    BHAVE, GG
    CRITICAL CARE MEDICINE, 1992, 20 (05) : 590 - 593
  • [22] TOPPITS: Trial Of Proton Pump Inhibitors in Throat Symptoms. Study protocol for a randomised controlled trial
    Gillian Watson
    James O’Hara
    Paul Carding
    Jan Lecouturier
    Deborah Stocken
    Tony Fouweather
    Janet Wilson
    Trials, 17
  • [23] TOPPITS: Trial Of Proton Pump Inhibitors in Throat Symptoms. Study protocol for a randomised controlled trial
    Watson, Gillian
    O'Hara, James
    Carding, Paul
    Lecouturier, Jan
    Stocken, Deborah
    Fouweather, Tony
    Wilson, Janet
    TRIALS, 2016, 17
  • [24] Stress ulcer prophylaxis versus placebo or no prophylaxis in adult hospitalised acutely ill patients-protocol for a systematic review with meta-analysis and trial sequential analysis
    Marker, Soren
    Perner, Anders
    Wetterslev, Jorn
    Barbateskovic, Marija
    Jakobsen, Janus Christian
    Krag, Mette
    Granholm, Anders
    Anthon, Carl Thomas
    Moller, Morten Hylander
    SYSTEMATIC REVIEWS, 2017, 6
  • [25] STRESS ULCER PROPHYLAXIS VERSUS PLACEBO IN CRITICALLY ILL PATIENTS. A SYSTEMATIC REVIEW OF RANDOMIZED CLINICAL TRIALS WITH META-ANALYSIS AND TRIAL SEQUENTIAL ANALYSIS
    Krag, M.
    Perner, A.
    Wetterslev, J.
    Wise, M. P.
    Moller, M. Hylander
    INTENSIVE CARE MEDICINE, 2013, 39 : S298 - S298
  • [26] Stress Ulcer Prophylaxis Versus Placebo-A Blinded Pilot Randomized Controlled Trial to Evaluate the Safety of Two Strategies in Critically Ill Infants With Congenital Heart Disease
    Mills, Kimberly I.
    Albert, Ben D.
    Bechard, Lori J.
    Chu, Stephen
    Duggan, Christopher P.
    Kaza, Aditya
    Rakoff-Nahoum, Seth
    Sleeper, Lynn A.
    Newburger, Jane W.
    Priebe, Gregory P.
    Mehta, Nilesh M.
    PEDIATRIC CRITICAL CARE MEDICINE, 2024, 25 (02) : 118 - 127
  • [27] Study protocol for a multicentre randomised controlled trial studying the effect of a music intervention on anxiety in adult critically ill patients (The RELACS trial)
    Kakar, Ellaha
    Van Mol, Margo
    Jeekel, Johannes
    Gommers, Diederik
    van der Jagt, Mathieu
    BMJ OPEN, 2021, 11 (10):
  • [28] Enteral nutrition as stress ulcer prophylaxis in critically ill patients: A randomized controlled exploratory study
    El-Kersh, Karim
    Jalil, Bilal
    McClave, Stephen A.
    Cavallazzi, Rodrigo
    Guardiola, Juan
    Guilkey, Karen
    Persaud, Annuradha K.
    Furmanek, Stephen P.
    Guinn, Brian E.
    Wiemken, Timothy L.
    Alhariri, Bashar Chihada
    Kellie, Scott P.
    Saad, Mohamed
    JOURNAL OF CRITICAL CARE, 2018, 43 : 108 - 113
  • [29] Cost-Effectiveness of Histamine2 Receptor Antagonists Versus Proton Pump Inhibitors for Stress Ulcer Prophylaxis in Critically Ill Patients
    Hammond, Drayton A.
    Kathe, Niranjan
    Shah, Anuj
    Martin, Bradley C.
    PHARMACOTHERAPY, 2017, 37 (01): : 43 - 53
  • [30] Stress ulcer prophylaxis with proton pump inhibitors or histamine 2 receptor antagonists in critically ill adults - a meta-analysis of randomized controlled trials with trial sequential analysis
    Xiaoyang Zhou
    Hanyuan Fang
    Jianfei Xu
    Peifu Chen
    Xujun Hu
    Bixin Chen
    Hua Wang
    Caibao Hu
    Zhaojun Xu
    BMC Gastroenterology, 19