Role of Nuclear Lamina in Gene Repression and Maintenance of Chromosome Architecture in the Nucleus

被引：0
|
作者：
Y. Y. Shevelyov
S. V. Ulianov
机构：
[1] Russian Academy of Sciences,Institute of Molecular Genetics
[2] Russian Academy of Sciences,Institute of Gene Biology
[3] Faculty of Biology,Lomonosov Moscow State University
来源：
Biochemistry (Moscow) | 2018年 / 83卷
关键词：
nuclear lamina; lamina-associated domain; nuclear envelope; nuclear periphery; repression;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Nuclear lamina is a protein meshwork composed of lamins and lamin-associated proteins that lines the nuclear envelope from the inside and forms repressive transcription compartment. The review presents current data on the contribution of nuclear lamina to the repression of genes located in this compartment and on the mechanisms of chromatin attachment to the nuclear envelope.
引用
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页码：359 / 369
页数：10
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