Cytochrome P450 isozymes 3A4 and 2B6 are involved in the in vitro human metabolism of thiotepa to TEPA

被引：0
|
作者：
P. Jacobson
K. Green
A. Birnbaum
R. Remmel
机构：
[1] Experimental and Clinical Pharmacology,
[2] College of Pharmacy,undefined
[3] 308 Harvard Street S.E.,undefined
[4] University of Minnesota,undefined
[5] Minneapolis,undefined
[6] MN 55455,undefined
[7] USA,undefined
[8] Medicinal Chemistry,undefined
[9] College of Pharmacy,undefined
[10] University of Minnesota,undefined
[11] Minneapolis,undefined
[12] MN,undefined
[13] USA,undefined
来源：
Cancer Chemotherapy and Pharmacology | 2002年 / 49卷
关键词：
Thiotepa TEPA Cytochrome P450 Metabolism Human microsomes;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：461 / 467
页数：6
相关论文
共 50 条
  • [41] An in vitro evaluation of human cytochrome P450 3A4 and P-glycoprotein inhibition by garlic
    Foster, BC
    Foster, MS
    Vandenhoek, S
    Krantis, A
    Budzinski, JW
    Arnason, JT
    Gallicano, KD
    Choudri, S
    JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES, 2001, 4 (02): : 176 - 184
  • [42] Aspergillus niger metabolism of citrus furanocoumarin inhibitors of human cytochrome P450 3A4
    Myung, Kyung
    Manthey, John A.
    Narciso, Jan A.
    APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2008, 78 (02) : 343 - 349
  • [43] Cytochrome P450 1A1/2, 2B6 and 3A4 HepaRG Cell-Based Biosensors to Monitor Hepatocyte Differentiation, Drug Metabolism and Toxicity
    Vlach, Manuel
    Quesnot, Nicolas
    Dubois-Pot-Schneider, Helene
    Ribault, Catherine
    Verres, Yann
    Petitjean, Kilian
    Rauch, Claudine
    Morel, Fabrice
    Robin, Marie-Anne
    Corlu, Anne
    Loyer, Pascal
    SENSORS, 2019, 19 (10):
  • [44] Testosterone 1β-hydroxylation by human cytochrome P450 3A4
    Krauser, JA
    Voehler, M
    Tseng, LH
    Schefer, AB
    Godejohann, M
    Guengerich, FP
    EUROPEAN JOURNAL OF BIOCHEMISTRY, 2004, 271 (19): : 3962 - 3969
  • [45] Testosterone 1β-hydroxylation by human cytochrome P450 3A4
    Krauser, JA
    Voehler, M
    Tseng, LH
    Schefer, AB
    Godejohann, M
    Guengerich, FP
    DRUG METABOLISM REVIEWS, 2004, 36 : 254 - 254
  • [46] Molecular modeling of cytochrome P450 3A4
    Szklarz, GD
    Halpert, JR
    JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN, 1997, 11 (03) : 265 - 272
  • [47] Herbal tea extracts inhibit Cytochrome P450 3A4 in vitro
    Dufay, Sophie
    Worsley, Alan
    Monteillier, Aymeric
    Avanzi, Charlotte
    Sy, Jaclyn
    Ng, Ting Fat
    Garcia, Jean-Michel
    Lam, Man-Fai
    Vanhoutte, Paul
    Wong, Ian C. K.
    JOURNAL OF PHARMACY AND PHARMACOLOGY, 2014, 66 (10) : 1478 - 1490
  • [48] Metabolism of cerivastatin by human liver microsomes in vitro - Characterization of primary metabolic pathways and of cytochrome P450 isozymes involved
    Boberg, M
    Angerbauer, R
    Fey, P
    Kanhai, WK
    Karl, W
    Kern, A
    Ploschke, J
    Radtke, M
    DRUG METABOLISM AND DISPOSITION, 1997, 25 (03) : 321 - 331
  • [49] Sertraline and cytochrome P450 3A4 in dysthymia
    Dunn, E
    Helpard, B
    Steiner, M
    BIOLOGICAL PSYCHIATRY, 1997, 41 : 116 - 116
  • [50] Molecular modeling of cytochrome P450 3A4
    Grazyna D. Szklarz
    James R. Halpert
    Journal of Computer-Aided Molecular Design, 1997, 11 : 265 - 272
12345