5-Formylcytosine does not change the global structure of DNA

被引：0

作者：

Jack S Hardwick

Denis Ptchelkine

Afaf H El-Sagheer

Ian Tear

Daniel Singleton

Simon E V Phillips

Andrew N Lane

Tom Brown

机构：

[1] University of Oxford,Department of Chemistry

[2] Chemistry Research Laboratory,Department of Science and Mathematics

[3] Research Complex at Harwell,Department of Biochemistry

[4] Rutherford Appleton Laboratory,Department of Toxicology and Cancer Biology

[5] Weatherall Institute of Molecular Medicine,undefined

[6] University of Oxford,undefined

[7] Chemistry Branch,undefined

[8] Faculty of Petroleum and Mining Engineering,undefined

[9] Suez University,undefined

[10] ATDBio,undefined

[11] School of Chemistry,undefined

[12] University of Southampton,undefined

[13] University of Oxford,undefined

[14] University of Kentucky,undefined

[15] Lexington,undefined

[16] Kentucky,undefined

[17] USA.,undefined

来源：

Nature Structural & Molecular Biology | 2017年 / 24卷

关键词：

D O I：

暂无

中图分类号：

学科分类号：

摘要：

X-ray crystallography and NMR analysis demonstrate that, contrary to previous observations, fC does not significantly alter DNA structure, thus suggesting an alternative basis for recognition of fC-DNA by epigenome-modifying enzymes.

引用

页码：544 / 552

页数：8

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