Loss of HER2 and decreased T-DM1 efficacy in HER2 positive advanced breast cancer treated with dual HER2 blockade: the SePHER Study

被引:0
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作者
Giulia Bon
Laura Pizzuti
Valentina Laquintana
Rossella Loria
Manuela Porru
Caterina Marchiò
Eriseld Krasniqi
Maddalena Barba
Marcello Maugeri-Saccà
Teresa Gamucci
Rossana Berardi
Lorenzo Livi
Corrado Ficorella
Clara Natoli
Enrico Cortesi
Daniele Generali
Nicla La Verde
Alessandra Cassano
Emilio Bria
Luca Moscetti
Andrea Michelotti
Vincenzo Adamo
Claudio Zamagni
Giuseppe Tonini
Giacomo Barchiesi
Marco Mazzotta
Daniele Marinelli
Silverio Tomao
Paolo Marchetti
Maria Rosaria Valerio
Rosanna Mirabelli
Antonio Russo
Maria Agnese Fabbri
Nicola D’Ostilio
Enzo Veltri
Domenico Corsi
Ornella Garrone
Ida Paris
Giuseppina Sarobba
Francesco Giotta
Carlo Garufi
Marina Cazzaniga
Pietro Del Medico
Mario Roselli
Giuseppe Sanguineti
Isabella Sperduti
Anna Sapino
Ruggero De Maria
Carlo Leonetti
Angelo Di Leo
机构
[1] IRCCS Regina Elena National Cancer Institute,Cellular Network and Molecular Therapeutic Target Unit
[2] IRCCS Regina Elena National Cancer Institute,Division of Medical Oncology 2
[3] IRCCS Regina Elena National CancerInstitute,Pathology Department
[4] IRCCS Regina Elena National Cancer Institute,Area of Translational Research
[5] University of Turin,Department of Medical Sciences
[6] Candiolo Cancer Institute,Medical Oncology
[7] FPO-IRCCS,Radiotherapy Unit, Department of Oncology
[8] Sandro Pertini Hospital,Medical Oncology Unit
[9] Oncology Clinic,Department of Medical, Oral and Biotechnological Sciences
[10] “Ospedali Riuniti di Ancona” Hospital,Department of Medical Oncology
[11] Careggi University Hospital,Oncology Unit, IRCCS Foundation Polyclinic University A. Gemelli
[12] St Salvatore Hospital,Department of Oncology and Hematology
[13] University Gabriele D’Annunzio,Medical Oncology Unit, A.O. Papardo & Department of Human Pathology
[14] University La Sapienza,Medical Oncology Unit, Addarii Institute of Oncology
[15] Breast Cancer Unit,Department of Oncology
[16] ASST Cremona,Medical Oncology Unit
[17] Oncology Unit,Department of Radiological, Oncological and Anatomo
[18] ASST Fatebenefratelli Sacco-PO Fatebenefratelli,Pathological Sciences
[19] University Cattolica Del Sacro Cuore,Medical Oncology
[20] University of Verona,Department of Ematology & Oncology
[21] University Hospital,Medical Oncology Unit
[22] UO Medical Oncology,Medical Oncology Unit
[23] S. Chiara Hospital,Gynaecology – Oncology Unit
[24] University of Messina,Department of Medical Oncology
[25] S. Orsola-Malpighi Hospital,Division of Medical Oncology
[26] University Campus Biomedico,Department of Systems Medicine
[27] Sant’Andrea University Hospital,Radiotherapy Department
[28] University La Sapienza,Department of Medical Oncology
[29] Umberto I University Hospital,Scientific Direction
[30] Paolo Giaccone University Hospital,undefined
[31] Pugliese-Ciaccio Hospital,undefined
[32] Medical Oncology Unit,undefined
[33] Belcolle Hospital,undefined
[34] Medical Oncology Unit,undefined
[35] Lanciano-Vasto,undefined
[36] Santa Maria Goretti Hospital,undefined
[37] Fatebenefratelli Hospital,undefined
[38] Medical Oncology AO S. Croce and Carle Teaching Hospital,undefined
[39] University Cattolica del Sacro Cuore,undefined
[40] Department of Medical Oncology,undefined
[41] ASL Nuro,undefined
[42] IRCCS Giovanni Paolo II,undefined
[43] Division of Medical Oncology,undefined
[44] Pescara Hospital,undefined
[45] Research Unit Phase I Trials and Oncology Unit,undefined
[46] ASST,undefined
[47] Reggio Calabria General Hospital,undefined
[48] Medical Oncology,undefined
[49] University Tor Vergata,undefined
[50] IRCCS Regina Elena National Cancer Institute,undefined
关键词
HER2+ breast cancer; Trastuzumab/pertuzumab blockade; T-DM1 efficacy;
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