Bach1 deficiency reduces severity of osteoarthritis through upregulation of heme oxygenase-1

被引:0
|
作者
Tsuyoshi Takada
Shigeru Miyaki
Hiroyuki Ishitobi
Yuya Hirai
Tomoyuki Nakasa
Kazuhiko Igarashi
Martin K. Lotz
Mitsuo Ochi
机构
[1] Hiroshima University,Department of Orthopedic Surgery, Graduate School of Biomedical Sciences
[2] Hiroshima University Hospital,Department of Regenerative Medicine
[3] Tohoku University Graduate School of Medicine,Department of Biochemistry
[4] The Scripps Research Institute,Department of Molecular and Experimental Medicine
关键词
Articular Cartilage; Medial Collateral Ligament; Articular Chondrocytes; Cartilage Homeostasis; Mouse Chondrocytes;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [21] Expression of heme oxygenase-1 in human leukemic cells and its regulation by transcriptional repressor Bach1
    Miyazaki, Takuya
    Kirino, Yohei
    Takeno, Mitsuhiro
    Samukawa, Sei
    Hama, Maasa
    Tanaka, Masatsugu
    Yamaji, Satoshi
    Ueda, Atsuhisa
    Tomita, Naoto
    Fujita, Hiroyuki
    Ishigatsubo, Yoshiaki
    CANCER SCIENCE, 2010, 101 (06) : 1409 - 1416
  • [22] TLR4 activation alters labile heme levels to regulate BACH1 and heme oxygenase-1 expression in macrophages
    Sudan, Kritika
    Vijayan, Vijith
    Madyaningrana, Kukuh
    Gueler, Faikah
    Igarashi, Kazuhiko
    Foresti, Roberta
    Motterlini, Roberto
    Immenschuh, Stephan
    FREE RADICAL BIOLOGY AND MEDICINE, 2019, 137 : 131 - 142
  • [23] Heme oxygenase-1 is repressed by Bach1: A novel heme-binding transcriptional repressor in smooth muscle cells and macrophages
    Omura, S
    Sun, JY
    Suzuki, H
    Toyofuku, M
    Igarashi, K
    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2003, 41 (06) : 314A - 314A
  • [24] Myocardial protection against pressure overload in mice lacking Bach1, a transcriptional repressor of heme oxygenase-1
    Mito, Shinji
    Ozono, Ryoji
    Oshima, Tetsuya
    Yano, Yoko
    Watari, Yuichiro
    Yamamoto, Yoshiyuki
    Brydun, Andrei
    Igarashi, Kazuhiko
    Yoshizumi, Masao
    HYPERTENSION, 2008, 51 (06) : 1570 - 1577
  • [25] BTB and CNC Homolog 1 (Bach1) Deficiency Ameliorates TNBS Colitis in Mice: Role of M2 Macrophages and Heme Oxygenase-1
    Harusato, Akihito
    Naito, Yuji
    Takagi, Tomohisa
    Uchiyama, Kazuhiko
    Mizushima, Katsura
    Hirai, Yasuko
    Higashimura, Yasuki
    Katada, Kazuhiro
    Handa, Osamu
    Ishikawa, Takeshi
    Yagi, Nobuaki
    Kokura, Satoshi
    Ichikawa, Hiroshi
    Muto, Akihiko
    Igarashi, Kazuhiko
    Yoshikawa, Toshikazu
    INFLAMMATORY BOWEL DISEASES, 2013, 19 (04) : 740 - 753
  • [26] The role of Bach1 in the induction of heme oxygenase by tin mesoporphyrin
    Abate, Aida
    Zhao, Hui
    Wong, Ronald J.
    Stevenson, David K.
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2007, 354 (03) : 757 - 763
  • [27] Role of BACH1 in regulation of heme oxygenase-1 in human liver: Insights from studies with siRNAs.
    Shan, Y
    Lambrecht, RW
    Ghaziani, T
    Dohohue, SE
    Bonkovsky, HL
    HEPATOLOGY, 2004, 40 (04) : 527A - 527A
  • [28] Pharmacological Targeting of Heme Oxygenase-1 in Osteoarthritis
    Sanada, Yohei
    Tan, Sho Joseph Ozaki
    Adachi, Nobuo
    Miyaki, Shigeru
    ANTIOXIDANTS, 2021, 10 (03) : 1 - 28
  • [29] Synergistic up-regulation of heme oxygenase-1 in human liver by heme and siRNA to Bach1: Possible therapeutic implications.
    Ghaziani, T
    Shan, Y
    Lambrecht, RW
    Bonkovsky, HL
    BLOOD, 2004, 104 (11) : 454A - 454A
  • [30] New biotechnological methods to reduce oxidative stress in the cardiovascular system: Focusing on the Bach1/heme oxygenase-1 pathway
    Ozono, R.
    CURRENT PHARMACEUTICAL BIOTECHNOLOGY, 2006, 7 (02) : 87 - 93