Virtual screening and experimental validation of novel histone deacetylase inhibitors

被引:0
|
作者
Yan-xin Huang
Jian Zhao
Qiu-hang Song
Li-hua Zheng
Cong Fan
Ting-ting Liu
Yong-li Bao
Lu-guo Sun
Li-biao Zhang
Yu-xin Li
机构
[1] Northeast Normal University,National Engineering Laboratory for Druggable Gene and Protein Screening
[2] School of Computer Science and Information Technology,Research Center of Agriculture and Medicine Gene Engineering of Ministry of Education
[3] Northeast Normal University,undefined
[4] Northeast Normal University,undefined
关键词
HDAC inhibitors; Pharmacophore; Docking; Virtual screening; Apoptosis;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [41] Chemistry and biology of mercaptoacetamides as novel histone deacetylase inhibitors
    Chen, B
    Petukhov, PA
    Jung, M
    Velena, A
    Eliseeva, E
    Dritschilo, A
    Kozikowski, AP
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2005, 15 (05) : 1389 - 1392
  • [42] Design and synthesis of a novel class of histone deacetylase inhibitors
    Lavoie, R
    Bouchain, G
    Frechette, S
    Woo, SH
    Abou Khalil, E
    Leit, S
    Fournel, M
    Yan, PT
    Trachy-Bourget, MC
    Beaulieu, C
    Li, ZM
    Besterman, J
    Delorme, D
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2001, 11 (21) : 2847 - 2850
  • [43] Histone Deacetylase Inhibitors: A Novel Strategy in Trauma and Sepsis
    Williams, Aaron M.
    Dennahy, Isabel S.
    Bhatti, Umar F.
    Biesterveld, Ben E.
    Graham, Nathan J.
    Li, Yongqing
    Alam, Hasan B.
    SHOCK, 2019, 52 (03): : 300 - 306
  • [44] High throughput screening identifies modulators of histone deacetylase inhibitors
    Ann-Christin Gaupel
    Thomas Begley
    Martin Tenniswood
    BMC Genomics, 15
  • [45] High throughput screening identifies modulators of histone deacetylase inhibitors
    Gaupel, Ann-Christin
    Begley, Thomas
    Tenniswood, Martin
    BMC GENOMICS, 2014, 15
  • [46] HIGH THROUGHPUT SCREENING OF NOVEL HISTONE DEACETYLASE INHIBITORS FOR EPIGENETIC THERAPY OF PRIMARY BRAIN TUMORS
    Marquardt, Viktoria
    Pauck, David
    Hansen, Finn K.
    Picard, Daniel
    Felsberg, Joerg
    Reifenberger, Guido
    Borkhardt, Arndt
    Kurz, Thomas
    Remke, Marc
    NEURO-ONCOLOGY, 2017, 19 : 57 - 58
  • [47] Novel Proteasome Inhibitors and Histone Deacetylase Inhibitors: Progress in Myeloma Therapeutics
    Chhabra, Saurabh
    PHARMACEUTICALS, 2017, 10 (02)
  • [48] COMP 140-Combinatorial QSAR analysis of histone deacetylase inhibitors and QSAR-based virtual screening
    Tang, Hao
    Wang, Xiang S.
    Huang, Xi-Ping
    Roth, Bryan L.
    Kozikowski, Alan P.
    Tropsha, Alexander
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2008, 235
  • [49] High-Throughput Screening of Novel Histone Deacetylase Inhibitors for Epigenetic Therapy of Primary Brain Tumors
    Marquardt, V.
    Hansen, F. K.
    Picard, D.
    Felsberg, J.
    Reifenberger, G.
    Borkhardt, A.
    Kurz, T.
    Remke, M.
    PEDIATRIC BLOOD & CANCER, 2016, 63 : S69 - S69
  • [50] Phenotypic Screening of Histone Deacetylase (HDAC) Inhibitors against Schistosoma mansoni
    Hassan, Muhammad Murtaza
    Sedighi, Abootaleb
    Olaoye, Olasunkanmi O.
    Haeberli, Cecile
    Merz, Annika
    Ramos-Morales, Elizabeth
    de Araujo, Elvin D.
    Romier, Christophe
    Jung, Manfred
    Keiser, Jennifer
    Gunning, Patrick T.
    CHEMMEDCHEM, 2022, 17 (18)