Mutational analysis of anal cancers demonstrates frequent PIK3CA mutations associated with poor outcome after salvage abdominoperineal resection

被引：0
|
作者：
Wulfran Cacheux
Etienne Rouleau
Adrien Briaux
Petros Tsantoulis
Pascale Mariani
Marion Richard-Molard
Bruno Buecher
Virginie Dangles-Marie
Sophie Richon
Julien Lazartigues
Emmanuelle Jeannot
Fereshteh Farkhondeh
Xavier Sastre-Garau
Anne de La Rochefordière
Alain Labib
Marie-Christine Falcou
Denise Stevens
Arnaud Roth
Sergio Roman-Roman
Emmanuel Mitry
Ivan Bièche
Astrid Lièvre
机构：
[1] Institut Curie,Department of Medical Oncology
[2] René Huguenin Hospital,Department of Genetics
[3] Pharmacogenomics Unit,Department of Surgical Oncology
[4] Institut Curie Hospital,Department of Radiation Oncology
[5] Center of Oncology,Department of Medical Oncology
[6] University Hospital of Geneva,Department of Pathology
[7] Institut Curie,Department of Radiation Oncology
[8] Institut Curie Hospital,Department of Public Health
[9] Institut Curie,Department of Gastroenterology
[10] Reneé Huguenin Hospital,undefined
[11] Institut Curie,undefined
[12] Institut Curie Hospital,undefined
[13] Translational Research,undefined
[14] Research Center,undefined
[15] Institut Curie,undefined
[16] IFR71,undefined
[17] Faculty of Biologic and Pharmacologic Sciences,undefined
[18] University Paris Descartes,undefined
[19] Sorbonne Paris Cité,undefined
[20] Institut Curie,undefined
[21] Institut Curie Hospital,undefined
[22] Institut Curie,undefined
[23] Institut Curie Hospital,undefined
[24] Institut Curie,undefined
[25] Institut Curie Hospital,undefined
[26] University Hospital of Rennes,undefined
[27] University of Rennes 1,undefined
来源：
British Journal of Cancer | 2016年 / 114卷
关键词：
anal squamous cell carcinoma; mutation status; PIK3CA; prognostic factor; abdominoperineal resection; therapeutic target;
D O I：
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中图分类号：
学科分类号：
摘要：
引用
收藏
页码：1387 / 1394
页数：7
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