Mutational analysis of anal cancers demonstrates frequent PIK3CA mutations associated with poor outcome after salvage abdominoperineal resection

被引：0

作者：

Wulfran Cacheux

Etienne Rouleau

Adrien Briaux

Petros Tsantoulis

Pascale Mariani

Marion Richard-Molard

Bruno Buecher

Virginie Dangles-Marie

Sophie Richon

Julien Lazartigues

Emmanuelle Jeannot

Fereshteh Farkhondeh

Xavier Sastre-Garau

Anne de La Rochefordière

Alain Labib

Marie-Christine Falcou

Denise Stevens

Arnaud Roth

Sergio Roman-Roman

Emmanuel Mitry

Ivan Bièche

Astrid Lièvre

机构：

[1] Institut Curie,Department of Medical Oncology

[2] René Huguenin Hospital,Department of Genetics

[3] Pharmacogenomics Unit,Department of Surgical Oncology

[4] Institut Curie Hospital,Department of Radiation Oncology

[5] Center of Oncology,Department of Medical Oncology

[6] University Hospital of Geneva,Department of Pathology

[7] Institut Curie,Department of Radiation Oncology

[8] Institut Curie Hospital,Department of Public Health

[9] Institut Curie,Department of Gastroenterology

[10] Reneé Huguenin Hospital,undefined

[11] Institut Curie,undefined

[12] Institut Curie Hospital,undefined

[13] Translational Research,undefined

[14] Research Center,undefined

[15] Institut Curie,undefined

[16] IFR71,undefined

[17] Faculty of Biologic and Pharmacologic Sciences,undefined

[18] University Paris Descartes,undefined

[19] Sorbonne Paris Cité,undefined

[20] Institut Curie,undefined

[21] Institut Curie Hospital,undefined

[22] Institut Curie,undefined

[23] Institut Curie Hospital,undefined

[24] Institut Curie,undefined

[25] Institut Curie Hospital,undefined

[26] University Hospital of Rennes,undefined

[27] University of Rennes 1,undefined

来源：

British Journal of Cancer | 2016年 / 114卷

关键词：

anal squamous cell carcinoma; mutation status; PIK3CA; prognostic factor; abdominoperineal resection; therapeutic target;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

引用

页码：1387 / 1394

页数：7

共 50 条

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