Effect of Rifampin on the Pharmacokinetics of Apixaban, an Oral Direct Inhibitor of Factor Xa

被引:0
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作者
Blisse Vakkalagadda
Charles Frost
Wonkyung Byon
Rebecca A. Boyd
Jessie Wang
Donglu Zhang
Zhigang Yu
Clapton Dias
Andrew Shenker
Frank LaCreta
机构
[1] Bristol-Myers Squibb Company,Research and Development, Discovery Medicine and Clinical Pharmacology
[2] Pfizer Inc,Global Innovative Pharma Business Clinical Pharmacology
[3] Bristol-Myers Squibb Company,Global Biometric Sciences
[4] Bristol-Myers Squibb Company,Pharmaceutical Candidate Optimization
关键词
Rifampin; Apixaban; Breast Cancer Resistance Protein; Absolute Oral Bioavailability; Single Ascend Dose Study;
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学科分类号
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页码:119 / 127
页数:8
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