Pharmacokinetics of Liposomal Gentamicin

被引：0
|
作者：
K. A. Rotov
S. N. Tikhonov
V. V. Alekseev
E. A. Snatenkov
机构：
[1] Russian Agency for Health and Consumer Rights,Volgograd Antiplague Institute
来源：
Bulletin of Experimental Biology and Medicine | 2012年 / 153卷
关键词：
antibiotics; liposomes; pharmacokinetics;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
We present data on pharmacokinetics of free and liposomal forms of gentamicin. Comparative study of two drug forms showed that immobilization of gentamicin in liposomes significantly increased most important pharmacokinetic parameters of the antibiotic (AUC, Сmax, MRTpo, Т1/2, Kel, Vzpo) and reduced Clpo and Kel.
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页码：475 / 477
页数：2
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