Experimental Evaluation of Combined Immunotherapy for Tumors

被引：0
|
作者：
I. Zh. Shubina
N. K. Akhmatova
F. V. Donenko
M. V. Kiselevskii
机构：
[1] Russian Academy of Medical Sciences,N. N. Blokhin Russian Cancer Research Center
[2] Russian Academy of Medical Sciences,I. I. Mechnikov Research Institute of Vaccines and Sera
来源：
Bulletin of Experimental Biology and Medicine | 2014年 / 157卷
关键词：
natural killer cells; dendritic cells; immunotherapy;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The minimal vaccination dose of tumor cells was determined on experimental models. The effectiveness of antitumor immunotherapy with activated natural killer cells or dendritic cell vaccine (monotherapy or combined treatment) was evaluated in vivo. The inhibition of tumor growth was more pronounced after combination therapy with activated natural killer cells and dendritic cell-based vaccine. Our results indicate that the effectiveness of antitumor immunotherapy increases in simultaneous modulation of both immune components (innate and adaptive immunity).
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页码：620 / 622
页数：2
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