(+)-[18F]Flubatine as a novel α4β2 nicotinic acetylcholine receptor PET ligand—results of the first-in-human brain imaging application in patients with β-amyloid PET-confirmed Alzheimer’s disease and healthy controls

被引：0
|
作者：
Solveig Tiepolt
Georg-Alexander Becker
Stephan Wilke
Diego Cecchin
Michael Rullmann
Philipp M. Meyer
Henryk Barthel
Swen Hesse
Marianne Patt
Julia Luthardt
Gudrun Wagenknecht
Bernhard Sattler
Winnie Deuther-Conrad
Friedrich-Alexander Ludwig
Steffen Fischer
Hermann-Josef Gertz
René Smits
Alexander Hoepping
Jörg Steinbach
Peter Brust
Osama Sabri
机构：
[1] University of Leipzig,Department of Nuclear Medicine
[2] University-Hospital of Padova,Department of Medicine
[3] Central Institute for Engineering,Electronic Systems (ZEA
[4] Electronics and Analytics,2)
[5] Research Centre Juelich,Helmholtz
[6] Research Site Leipzig,Zentrum Dresden
[7] University of Leipzig,Rossendorf
[8] ABX advanced biochemical compounds GmbH,Department of Psychiatry
[9] Helmholtz-Zentrum Dresden-Rossendorf,undefined
来源：
European Journal of Nuclear Medicine and Molecular Imaging | 2021年 / 48卷
关键词：
(+)-[; F]Flubatine [(+)-[; F]NCFHEB]; PET; α4β2 nicotinic acetylcholine receptors; Human brain; Kinetic modeling;
D O I：
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中图分类号：
学科分类号：
摘要：
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收藏
页码：731 / 746
页数：15
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