(+)-[18F]Flubatine as a novel α4β2 nicotinic acetylcholine receptor PET ligand—results of the first-in-human brain imaging application in patients with β-amyloid PET-confirmed Alzheimer’s disease and healthy controls

被引：0

作者：

Solveig Tiepolt

Georg-Alexander Becker

Stephan Wilke

Diego Cecchin

Michael Rullmann

Philipp M. Meyer

Henryk Barthel

Swen Hesse

Marianne Patt

Julia Luthardt

Gudrun Wagenknecht

Bernhard Sattler

Winnie Deuther-Conrad

Friedrich-Alexander Ludwig

Steffen Fischer

Hermann-Josef Gertz

René Smits

Alexander Hoepping

Jörg Steinbach

Peter Brust

Osama Sabri

机构：

[1] University of Leipzig,Department of Nuclear Medicine

[2] University-Hospital of Padova,Department of Medicine

[3] Central Institute for Engineering,Electronic Systems (ZEA

[4] Electronics and Analytics,2)

[5] Research Centre Juelich,Helmholtz

[6] Research Site Leipzig,Zentrum Dresden

[7] University of Leipzig,Rossendorf

[8] ABX advanced biochemical compounds GmbH,Department of Psychiatry

[9] Helmholtz-Zentrum Dresden-Rossendorf,undefined

来源：

European Journal of Nuclear Medicine and Molecular Imaging | 2021年 / 48卷

关键词：

(+)-[; F]Flubatine [(+)-[; F]NCFHEB]; PET; α4β2 nicotinic acetylcholine receptors; Human brain; Kinetic modeling;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

引用

页码：731 / 746

页数：15

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