Evolution of Proteins of the DNA Photolyase/Cryptochrome Family

被引:0
|
作者
Yu. L. Vechtomova
T. A. Telegina
M. S. Kritsky
机构
[1] Russian Academy of Sciences,Bach Institute of Biochemistry, Federal Research Center of Biotechnology
来源
Biochemistry (Moscow) | 2020年 / 85卷
关键词
DNA photolyase; cryptochrome; evolution; LUCA;
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学科分类号
摘要
Proteins of the cryptochrome/DNA photolyase family (CPF) are phylogenetically related and structurally conserved flavoproteins that perform various functions. DNA photolyases repair DNA damage caused by UV-B radiation by exposure to UV-A/blue light simultaneously or subsequently. Cryptochromes are photoreceptor proteins regulating circadian clock, morphogenesis, phototaxis, and other responses to UV and blue light in various organisms. The review describes the structure and functions of CPF proteins, their evolutionary relationship, and possible functions of the CPF ancestor protein.
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页码:131 / 153
页数:22
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