Naive and memory B cells in T-cell-dependent and T-independent responses

被引:0
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作者
Rudolf H. Zubler
机构
[1] Geneva University Hospital,Division of Hematology
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关键词
Germinal Center; Marginal Zone; Natural Antibody; Affinity Maturation; Receptor Editing;
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摘要
This review focuses on the properties and roles of distinct subsets among the primary and the memory B lymphocytes regarding their contribution to helper-T-cell-dependent and -independent antibody responses. The naive/memory B cell functions are explained in the context of current concepts on the basic mechanisms of humoral immunity. Differences between murine and human B cells are also discussed.
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页码:405 / 419
页数:14
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