Ductal pancreatic cancer modeling and drug screening using human pluripotent stem cell– and patient-derived tumor organoids

被引：0
|
作者：
Ling Huang
Audrey Holtzinger
Ishaan Jagan
Michael BeGora
Ines Lohse
Nicholas Ngai
Cristina Nostro
Rennian Wang
Lakshmi B Muthuswamy
Howard C Crawford
Cheryl Arrowsmith
Steve E Kalloger
Daniel J Renouf
Ashton A Connor
Sean Cleary
David F Schaeffer
Michael Roehrl
Ming-Sound Tsao
Steven Gallinger
Gordon Keller
Senthil K Muthuswamy
机构：
[1] Princess Margaret Cancer Center,Department of Physiology
[2] University Health Network (UHN),Department of Pharmacology
[3] University of Toronto,Department of Molecular and Integrative Physiology
[4] McEwen Center for Regenerative Medicine,Department of Internal Medicine
[5] University Health Network,Division of Anatomic Pathology
[6] Western University,Department of Medicine
[7] Western University,Division of Medical Oncology
[8] University of Michigan,Division of General Surgery
[9] University of Michigan,Department of Pathology
[10] Structural Genomics Consortium,undefined
[11] Vancouver General Hospital,undefined
[12] The University of British Columbia,undefined
[13] Pancreas Centre British Columbia,undefined
[14] British Columbia Cancer Agency,undefined
[15] University of Toronto,undefined
[16] University Health Network,undefined
来源：
Nature Medicine | 2015年 / 21卷
关键词：
D O I：
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中图分类号：
学科分类号：
摘要：
Human pluripotent stem cells can be differentiated into exocrine pancreas progenitor organoids, allowing studies of development and pancreatic cancer modeling.
引用
收藏
页码：1364 / 1371
页数：7
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