Metabolic exit from naive pluripotency

被引：0
|
作者：
Jun Wu
Juan Carlos Izpisua Belmonte
机构：
[1] Jun Wu and Juan Carlos Izpisua Belmonte are at the Gene Expression Laboratory,
[2] The Salk Institute for Biological Studies,undefined
[3] 10010 N. Torrey Pines Road,undefined
[4] La Jolla,undefined
[5] California 92037,undefined
[6] USA,undefined
来源：
Nature Cell Biology | 2015年 / 17卷
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Spatiotemporally distinct pluripotent states captured in vitro provide an accessible way of modelling early human development. An intricate interplay between the metabolome and histone modifications is now shown to drive the metabolic switch from human naive to primed pluripotency, one of the earliest steps of embryogenesis.
引用
收藏
页码：1519 / 1521
页数：2
相关论文
共 50 条
  • [41] Metabolic RemodeLIN of Pluripotency
    Mathieu, Julie
    Ruohola-Baker, Hannele
    CELL STEM CELL, 2016, 19 (01) : 3 - 4
  • [42] Ctbp2-mediated β-catenin regulation is required for exit from pluripotency
    Kim, Tae Wan
    Kwak, Sojung
    Shin, Jihoon
    Kang, Byung-Hee
    Lee, Sang-Eun
    Suh, Min Young
    Kim, Jae-Hwan
    Hwang, In-Young
    Lee, Jong-Hyuk
    Choi, Jinmi
    Cho, Eun-Jung
    Youn, Hong-Duk
    EXPERIMENTAL AND MOLECULAR MEDICINE, 2017, 49 : e385 - e385
  • [43] Ctbp2-mediated β-catenin regulation is required for exit from pluripotency
    Tae Wan Kim
    Sojung Kwak
    Jihoon Shin
    Byung-Hee Kang
    Sang-Eun Lee
    Min Young Suh
    Jae-Hwan Kim
    In-Young Hwang
    Jong-Hyuk Lee
    Jinmi Choi
    Eun-Jung Cho
    Hong-Duk Youn
    Experimental & Molecular Medicine, 2017, 49 : e385 - e385
  • [44] Genome-Scale Oscillations in DNA Methylation during Exit from Pluripotency
    Rulands, Steffen
    Lee, Heather J.
    Clark, Stephen J.
    Angermueller, Christof
    Smallwood, Sebastien A.
    Krueger, Felix
    Mohammed, Hisham
    Dean, Wendy
    Nichols, Jennifer
    Rugg-Gunn, Peter
    Kelsey, Gavin
    Stegle, Oliver
    Simons, Benjamin D.
    Reik, Wolf
    CELL SYSTEMS, 2018, 7 (01) : 63 - +
  • [45] Noncanonical function of DGCR8 controls mESC exit from pluripotency
    Cirera-Salinas, Daniel
    Yu, Jian
    Bodak, Maxime
    Ngondo, Richard P.
    Herbert, Kristina M.
    Ciaudo, Constance
    JOURNAL OF CELL BIOLOGY, 2017, 216 (02): : 355 - 366
  • [46] Naive pluripotency is associated with global DNA hypomethylation
    Leitch, Harry G.
    McEwen, Kirsten R.
    Turp, Aleksandra
    Encheva, Vesela
    Carroll, Tom
    Grabole, Nils
    Mansfield, William
    Nashun, Buhe
    Knezovich, Jaysen G.
    Smith, Austin
    Surani, M. Azim
    Hajkova, Petra
    NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2013, 20 (03) : 311 - 316
  • [47] microRNAs Regulating Human and Mouse Naive Pluripotency
    Wang, Yuliang
    Hussein, Abdiasis M.
    Somasundaram, Logeshwaran
    Sankar, Rithika
    Detraux, Damien
    Mathieu, Julie
    Ruohola-Baker, Hannele
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2019, 20 (23)
  • [48] Signaling Roadmap Modulating Naive and Primed Pluripotency
    Hassani, Seyedeh-Nafiseh
    Totonchi, Mehdi
    Gourabi, Hamid
    Schoeler, Hans R.
    Baharvand, Hossein
    STEM CELLS AND DEVELOPMENT, 2014, 23 (03) : 193 - 208
  • [49] Naive pluripotency is associated with global DNA hypomethylation
    Harry G Leitch
    Kirsten R McEwen
    Aleksandra Turp
    Vesela Encheva
    Tom Carroll
    Nils Grabole
    William Mansfield
    Buhe Nashun
    Jaysen G Knezovich
    Austin Smith
    M Azim Surani
    Petra Hajkova
    Nature Structural & Molecular Biology, 2013, 20 : 311 - 316
  • [50] Capturing Human Naive Pluripotency in the Embryo and in the Dish
    Zimmerlin, Ludovic
    Park, Tea Soon
    Zambidis, Elias T.
    STEM CELLS AND DEVELOPMENT, 2017, 26 (16) : 1141 - 1161
12345