Metabolic exit from naive pluripotency

被引：0
|
作者：
Jun Wu
Juan Carlos Izpisua Belmonte
机构：
[1] Jun Wu and Juan Carlos Izpisua Belmonte are at the Gene Expression Laboratory,
[2] The Salk Institute for Biological Studies,undefined
[3] 10010 N. Torrey Pines Road,undefined
[4] La Jolla,undefined
[5] California 92037,undefined
[6] USA,undefined
来源：
Nature Cell Biology | 2015年 / 17卷
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摘要：
Spatiotemporally distinct pluripotent states captured in vitro provide an accessible way of modelling early human development. An intricate interplay between the metabolome and histone modifications is now shown to drive the metabolic switch from human naive to primed pluripotency, one of the earliest steps of embryogenesis.
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页码：1519 / 1521
页数：2
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