Preclinical Evaluation of Anti-HIV-1 Polybiguanide Vaginal Microbicides in a Murine Model of Toxicity and Inflammation

被引：0
|
作者：
Tina Kish-Catalone
Mohamed E Labib
Robert F Rando
Brian Wigdahl
Fred C Krebs
机构：
[1] Drexel University College of Medicine,Department of Microbiology and Immunology, and Institute for Molecular Medicine and Infectious Disease
[2] Novaflux Biosciences,undefined
[3] Inc.,undefined
来源：
Retrovirology | / 2卷
关键词：
Inflammatory Response; Temporal Difference; Safety Profile; Murine Model; Specific Marker;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [41] In vivo evaluation of a mucoadhesive polymeric caplet for intravaginal anti-HIV-1 delivery and development of a molecular mechanistic model for thermochemical characterization
    Ndesendo, Valence M. K.
    Choonara, Yahya E.
    Meyer, Leith C. R.
    Kumar, Pradeep
    Tomar, Lomas K.
    Tyagi, Charu
    du Toit, Lisa C.
    Pillay, Viness
    DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, 2015, 41 (08) : 1274 - 1287
  • [42] Evaluation of the affinity measurement of anti-HIV-1 p17 monoclonal antibody by BIAcore
    Ota, A
    Ueda, S
    HYBRIDOMA, 1998, 17 (05): : 471 - 477
  • [43] Design, synthesis and anti-HIV-1 evaluation of novel substituted uracil derivatives as potent NNRTIs
    Ordonez, P.
    Hamasaki, T.
    Isono, Y.
    Ikejiri, M.
    Sakakibara, N.
    Maruyama, T.
    Baba, M.
    EUROPEAN JOURNAL OF MEDICAL RESEARCH, 2010, 15 (08) : 333 - 333
  • [44] EVALUATION OF COMMERCIAL ENZYME IMMUNOASSAYS FOR ANTI-HIV-1 USING EAST-AFRICAN SERA
    BREDBERGRADEN, U
    KIANGO, J
    MHALU, F
    BIBERFELD, G
    AIDS, 1988, 2 (04) : 281 - 285
  • [45] Topical gel formulation of broadly neutralizing anti-HIV-1 monoclonal antibody VRC01 confers protection against HIV-1 vaginal challenge in a humanized mouse model
    Veselinovic, Milena
    Neff, C. Preston
    Mulder, Leila R.
    Akkina, Ramesh
    VIROLOGY, 2012, 432 (02) : 505 - 510
  • [46] Synthesis and anti-HIV-1 evaluation of 1,5-disubstituted pyrimidine-2,4-diones
    Loksha, Yasser M.
    Globisch, Daniel
    Pedersen, Erik B.
    La Colla, Paolo
    Collu, Gabriella
    Loddo, Roberta
    JOURNAL OF HETEROCYCLIC CHEMISTRY, 2008, 45 (04) : 1161 - 1166
  • [47] CONSTRUCTION OF A MURINE RETROVIRAL VECTOR EXPRESSING AN ANTI-HIV-1 RIBOZYME AS PART OF A LACZ GENE WITH SPECIFIC PACKAGING USING THE HIV-1 ENVELOPE
    JACKSON, WH
    MOSCOSO, H
    NECHTMAN, JF
    LANCLOS, KD
    GARVER, FA
    BLOOD, 1994, 84 (10) : A741 - A741
  • [48] Raft-tropic antivirals: 1 synthesis and anti-HIV-1 evaluation of cholesten-containing polyanions
    Egorov, Y.
    Serbin, A.
    Alikhanova, O.
    Burshtein, M.
    Lupandin, S.
    Bukrinskaya, A.
    ANTIVIRAL RESEARCH, 2007, 74 (03) : A49 - A49
  • [49] Synthesis and evaluation of N-aryl pyrrolidinones as novel anti-HIV-1 agents.: Part 1
    Wu, Baogen
    Kuhen, Kelli
    Nguyen, Truc Ngoc
    Ellis, David
    Anaclerio, Beth
    He, Xiaohui
    Yang, Kunyong
    Karanewsky, Donald
    Yin, Hong
    Wolff, Karen
    Bieza, Kimberly
    Caldwell, Jeremy
    He, Yun
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2006, 16 (13) : 3430 - 3433
  • [50] Antiangiogenic, antitumoural and antimetastatic effects of two distamycin A derivatives with anti-HIV-1 Tat activity in a Kaposi's sarcoma-like murine model
    Laura Possati
    Diana Campioni
    Francesco Sola
    Luciana Leone
    Luigi Ferrante
    Cecilia Trabanelli
    Marina Ciomei
    Marco Montesi
    Romina Rocchetti
    Simona Talevi
    Stefano Bompadre
    Antonella Caputo
    Giuseppe Barbanti-Brodano
    Alfredo Corallini
    Clinical & Experimental Metastasis, 1999, 17 : 575 - 582
12345