p53 guards the metabolic pathway less travelled

被引：0

作者：

Eyal Gottlieb

机构：

[1] Eyal Gottlieb is at Cancer Research UK,

[2] The Beatson Institute for Cancer Research,undefined

[3] Glasgow,undefined

[4] G61 1BD,undefined

[5] UK. e.gottlieb@beatson.gla.ac.uk,undefined

来源：

Nature Cell Biology | 2011年 / 13卷

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学科分类号：

摘要：

Glucose is an important source of energy and carbon, and is required for cell growth. As such, glucose utilization is increased in rapidly dividing cancer cells. The tumour suppressor p53 has now been reported to block a metabolic pathway (the pentose phosphate pathway) that diverts glucose away from bioenergetic into biosynthetic routes.

引用

页码：195 / 197

页数：2

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