Treatment with a gonadotropin-releasing-hormone analog and attainment of full height potential in a male monozygotic twin with gonadotropin-releasing hormone-dependent precocious puberty

被引:0
|
作者
T. Ishii
S. Sato
M. Anzo
G. Sasaki
T. Hasegawa
S. Tamai
N. Matsuo
机构
[1] Department of Pediatrics,
[2] Keio University School of Medicine,undefined
[3] 35 Shinanomachi,undefined
[4] Shinjuku-ku,undefined
[5] Tokyo 60-8582,undefined
[6] Japan e-mail: t-ishii@med.keio.ac.jp,undefined
[7] Tel.: +81-3-33531211,undefined
[8] Fax: +81-3-53791978,undefined
来源
European Journal of Pediatrics | 1999年 / 158卷
关键词
Key words Precocious puberty; Hypothalamic hamartoma; Monozygotic twins; GnRH analog; Final height;
D O I
暂无
中图分类号
学科分类号
摘要
We report on a pair of male monozygotic twins, one unaffected and the other affected with gonadotropin-releasing hormone (GnRH)-dependent precocious puberty, and discuss the role of treatment with a GnRH analog in the attainment of full height potential in GnRH-dependent precocious puberty. At 1.6 years of age, the affected twin was studied for tall stature (+3.8 SD), and was diagnosed as having GnRH-dependent precocious puberty due to a hypothalamic hamartoma of the tuber cinereum. He was treated with oral cyproterone acetate (110–170 mg/m2 daily) from 1.8 through 5.0 years of age, with oral cyproterone acetate and intranasal buserelin acetate (700–900 μg/m2 daily) from 5.0 through 7.5 years, and with intranasal buserelin acetate alone (1100– 1400 μg/m2 daily) from 7.5 through 12.6 years. He attained a final height of 171.0 cm at 14.9 years of age (+0.10 SD) and his twin 170.0 cm at 15.3 years of age (−0.10 SD), with their target height being 174.5 ± 9.0 cm.
引用
收藏
页码:933 / 935
页数:2
相关论文
共 50 条
  • [41] USE OF GONADOTROPIN-RELEASING-HORMONE ANALOG IN TREATMENT OF EXHIBITIONISM
    MARCUS, AO
    FERNANDEZ, MP
    DEKEYSER, L
    CLINICAL RESEARCH, 1993, 41 (01): : A107 - A107
  • [42] Effect of Gonadotropin-Releasing Hormone Agonist Treatment in Boys with Central Precocious Puberty and Early Puberty
    Kim, Eun Young
    Yi, Kyung Hee
    Lee, Jae Hee
    HORMONE RESEARCH IN PAEDIATRICS, 2018, 90 : 581 - 581
  • [43] Gonadotropin-releasing hormone analogs treatment in girls with central precocious puberty and early fast puberty
    Lerman, Leiat
    Yackobovitch-Gavan, Michal
    Phillip, Moshe
    Shalitin, Shlomit
    PEDIATRIC RESEARCH, 2024, 95 (04) : 1051 - 1059
  • [44] THE EFFECT OF GONADOTROPIN-RELEASING HORMONE ANALOG ON HEIGHT PROGNOSIS IN GROWTH-HORMONE DEFICIENCY AND NORMAL PUBERTY
    STANHOPE, R
    BROOK, CGD
    EUROPEAN JOURNAL OF PEDIATRICS, 1988, 148 (03) : 200 - 202
  • [45] Gonadotropin-releasing hormone analogs treatment in girls with central precocious puberty and early fast puberty
    Leiat Lerman
    Michal Yackobovitch-Gavan
    Moshe Phillip
    Shlomit Shalitin
    Pediatric Research, 2024, 95 : 1051 - 1059
  • [46] LONG-TERM EFFECTIVENESS OF DEPOT GONADOTROPIN-RELEASING-HORMONE ANALOG IN THE TREATMENT OF CHILDREN WITH CENTRAL PRECOCIOUS PUBERTY
    CLEMONS, RD
    KAPPY, MS
    STUART, TE
    PERELMAN, AH
    HOEKSTRA, FT
    AMERICAN JOURNAL OF DISEASES OF CHILDREN, 1993, 147 (06): : 653 - 657
  • [47] Electrocardiogram Changes Following the Treatment with Gonadotropin-Releasing Hormone Agonists in Patients with Precocious Puberty
    Shiva, Siamak
    Samadi, Mahmoud
    Bagherzadeh, Ali
    Sadat-Ebrahimi, Seyyed-Reza
    INTERNATIONAL JOURNAL OF PEDIATRICS-MASHHAD, 2021, 9 (11): : 14867 - 14876
  • [48] Factors determining normal adult height in girls with gonadotropin-dependent precocious puberty treated with depot gonadotropin-releasing hormone analogs
    Brito, Vinicius Nahime
    Latronico, Ana Claudia
    Cukier, Priscilla
    Teles, Milena Gurgel
    Silveira, Leticia F. G.
    Prado Arnhold, Ivo Jorge
    Mendonca, Berenice Bilharinho
    JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2008, 93 (07): : 2662 - 2669
  • [49] Psychological effects of gonadotropin-releasing hormone agonist treatment in girls with central precocious puberty
    Yu, Rita
    Yang, Seung
    Hwang, Il Tae
    JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM, 2019, 32 (10): : 1071 - 1075
  • [50] OUTCOMES OF GONADOTROPIN-RELEASING HORMONE AGONIST TREATMENT IN OBESE GIRLS WITH CENTRAL PRECOCIOUS PUBERTY
    Kim, Hye Ryun
    Nam, Hyo-Kyoung
    Rhie, Young-Jun
    Lee, Kee-Hyoung
    HORMONE RESEARCH IN PAEDIATRICS, 2017, 88 : 356 - 356