Allelic frequencies of twelve dinucleotide repeat marker loci on chromosome 13 in the normal Japanese population

被引:0
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作者
Yuka Yamane
Yusuke Nakamura
Minoru Isomura
机构
[1] The University of Tokyo,Laboratory of Molecular Medicine, Institute of Medical Science
[2] Foundation for Cancer Research,Department of Human Genome Analysis, The Cancer Chemotherapy Center
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关键词
microsatellite marker; allelic distribution; linkage analysis;
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学科分类号
摘要
To establish a genotypic database for dinucleotide repeat marker loci in the Japanese population, we determined allelic frequencies of 12 such markers on chromosome 13 and compared them with data from Caucasians in the GDB archive. The average heterozygosity (79%) for the 12 loci was the same for the two populations. However, allelic distributions at two of the marker loci were quite different. These data will be useful for disease studies in the Japanese population that involve linkage or sibship-pair analyses, or association studies.
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页码:533 / 537
页数:4
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