Fluorinated [1,2,4]triazolo[1,5-a]pyrimidines and [1,2,4]triazolo[5,1-c][1,2,4]triazines*

被引：0
|
作者：
E. N. Ulomskiy
N. R. Medvedeva
A. V. Shchepochkin
O. S. Eltsov
V. L. Rusinov
O. N. Chupakhin
E. G. Deeva
O. I. Kiselev
机构：
[1] Ural Federal University,I. Ya. Postovsky Institute of Organic Synthesis
[2] Ural Branch of the Russian Academy of Sciences,Research Institute of Influenza
[3] Russian Academy of Medical Sciences,undefined
来源：
Chemistry of Heterocyclic Compounds | 2011年 / 47卷
关键词：
fluorinated azines; [1,2,4]triazolo[1,5-; ]pyrimidin-7(4H)-ones; [1,2,4]triazolo[5,1-; ][1,2,4]-triazin-4(1H)-ones;
D O I：
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学科分类号：
摘要：
The reaction of 3-R-5-amino-1,2,4-triazoles with the ethyl ester of 2-fluoroacetoacetic acid gave 2-R-fluoro[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-ones. The reaction of a 3-R-1,2,4-triazolyl-5-diazonium salt with the ethyl ester of 2-fluoroacetoacetic acid and subsequent cyclization of the triazolylhydrazones lead to 7-R-3-fluoro[1,2,4]triazolo[5,1-c][1,2,4]triazin-4(1H)-ones.
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页码：1164 / 1169
页数：5
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