Adsorption of components of enzymatic synthesis of ampicillin on different hydrophobic resins

被引：0
|
作者：
Marcelo F. Vieira
Marlei Barboza
Raquel de Lima C. Giordano
机构：
[1] Universidade Federal de São Carlos,Departamento de Engenharia Química
[2] UNAERP,Departamento de Engenharia Química
[3] Universidade de Ribeirão Preto,undefined
来源：
Applied Biochemistry and Biotechnology | 2003年 / 108卷 / 1-3期
关键词：
Ampicillin; purification; adsorption; β-lactamics;
D O I：
10.1385/ABAB:108:1-3:705
中图分类号：
学科分类号：
摘要：
This work compared the performance of three hydrophobic resins for the adsorption of ampicillin (AMP), d-phenylglycine (PG), d-phenylglycine methyl ester (PGME), and 6-aminopenicillanic acid (6-APA). The influence of pH on adsorption efficiencies was assessed in the range of 4.5–8.5, at 4 and 25°C. The values at 4°C were slightly higher than those at 25°C. The adsorption efficiency of AMP and 6-APA decreased at higher pHs, for the three resins. An opposite behavior was found for PGME, and the pH did not affect PG adsorption efficiency. Isotherm models were fitted to experimental equilibrium data and the best models were discriminated.
引用
收藏
页码：705 / 713
页数：8
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