Adsorption of components of enzymatic synthesis of ampicillin on different hydrophobic resins

被引：0
|
作者：
Marcelo F. Vieira
Marlei Barboza
Raquel de Lima C. Giordano
机构：
[1] Universidade Federal de São Carlos,Departamento de Engenharia Química
[2] UNAERP,Departamento de Engenharia Química
[3] Universidade de Ribeirão Preto,undefined
来源：
Applied Biochemistry and Biotechnology | 2003年 / 108卷 / 1-3期
关键词：
Ampicillin; purification; adsorption; β-lactamics;
D O I：
10.1385/ABAB:108:1-3:705
中图分类号：
学科分类号：
摘要：
This work compared the performance of three hydrophobic resins for the adsorption of ampicillin (AMP), d-phenylglycine (PG), d-phenylglycine methyl ester (PGME), and 6-aminopenicillanic acid (6-APA). The influence of pH on adsorption efficiencies was assessed in the range of 4.5–8.5, at 4 and 25°C. The values at 4°C were slightly higher than those at 25°C. The adsorption efficiency of AMP and 6-APA decreased at higher pHs, for the three resins. An opposite behavior was found for PGME, and the pH did not affect PG adsorption efficiency. Isotherm models were fitted to experimental equilibrium data and the best models were discriminated.
引用
收藏
页码：705 / 713
页数：8
相关论文
共 50 条
  • [1] Adsorption of components of enzymatic synthesis of ampicillin on different hydrophobic resins
    Vieira, MF
    Barboza, M
    Giordano, RDC
    APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY, 2003, 105 : 705 - 713
  • [2] Selective adsorption of flavor-active components on hydrophobic resins
    Saffarionpour, Shima
    Sevillano, David Mendez
    Van der Wielen, Luuk A. M.
    Noordman, T. Reinoud
    Brouwer, Eric
    Ottens, Marcel
    JOURNAL OF CHROMATOGRAPHY A, 2016, 1476 : 25 - 34
  • [3] Enzymatic reactive crystallization for improving ampicillin synthesis
    McDonald, Matthew A.
    Bommarius, Andreas S.
    Rousseau, Ronald W.
    CHEMICAL ENGINEERING SCIENCE, 2017, 165 : 81 - 88
  • [4] Efficient enzymatic synthesis of ampicillin in organic media
    Pan, Sheng-Bin
    Wu, Qi
    Chen, Chun-Xiu
    Lin, Xian-Fu
    JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC, 2008, 54 (1-2) : 13 - 18
  • [5] ENZYMATIC-SYNTHESIS OF AMPICILLIN - A CHEMOMETRIC OPTIMIZATION
    BOCCU, E
    EBERT, C
    GARDOSSI, L
    GIANFERRARA, T
    ZACCHIGNA, M
    LINDA, P
    FARMACO, 1991, 46 (04): : 565 - 577
  • [6] Enzymatic synthesis of ampicillin in precipitated medium with different acyl donor derivatives: perspectives for industrial application
    Giordano, R.
    Ribeiro, M.
    Giordano, R.
    Batigalhia, F.
    Leite, G.
    NEW BIOTECHNOLOGY, 2009, 25 : S165 - S165
  • [7] Evaluation of immunoglobulin adsorption on the hydrophobic charge-induction resins with different ligand densities and pore sizes
    Lu, Hui-Li
    Lin, Dong-Qiang
    Gao, Dong
    Yao, Shan-Jing
    JOURNAL OF CHROMATOGRAPHY A, 2013, 1278 : 61 - 68
  • [8] ENZYMATIC-SYNTHESIS OF HYDROPHOBIC PENICILLINS
    LUENGO, JM
    JOURNAL OF ANTIBIOTICS, 1995, 48 (11): : 1195 - 1212
  • [9] The Adsorption Effect of Different Resins with Epothilones
    Cao, Jian
    Li, Can
    Li, Kun-lun
    Liu, Xin-li
    Zhao, Lin
    2018 3RD INTERNATIONAL CONFERENCE ON AUTOMATION, MECHANICAL AND ELECTRICAL ENGINEERING (AMEE 2018), 2018, 298 : 447 - 452
  • [10] On the adsorption of hyaluronan and ICAM-1 to modified hydrophobic resins
    McCourt, PAG
    Gustafson, S
    INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, 1997, 29 (10): : 1179 - 1189
12345