Effect of a Single Dose of Levodopa on Sexual Response in Men and Women

被引:0
|
作者
Stephanie Both
Walter Everaerd
Ellen Laan
Louis Gooren
机构
[1] University of Amsterdam,Department of Clinical Psychology, Faculty of Social and Behavioral Sciences
[2] Academic Hospital,Department of Psychosomatic Gynecology and Sexology
[3] Leiden University,Department of Internal Medicine
[4] Academic Hospital,undefined
[5] Free University,undefined
来源
Neuropsychopharmacology | 2005年 / 30卷
关键词
motivation; sexual arousal; reflex modulation; dopamine; levodopa;
D O I
暂无
中图分类号
学科分类号
摘要
From animal research, there is ample evidence for a facilitating effect of dopamine on sexual behavior. In humans, little experimental research has been conducted on the inter-relation between dopamine and sexual response, even less so in women than in men. We investigated the effect of levodopa (100 mg) on sexual response in men and women following a double-blind, placebo-controlled crossover design. Genital and subjective sexual responses were measured as well as somatic motor system activity by means of Achilles tendon (T) reflex modulation. Genital and subjective sexual arousal were not affected by levodopa. However, the drug increased T reflex magnitude in response to sexual stimulation in men, but not in women. These results support the view that dopamine is involved in the energetic aspects of appetitive sexual behavior in men. The observed gender difference in the effect of levodopa is discussed in the perspective of possible dopamine–steroid interaction.
引用
收藏
页码:173 / 183
页数:10
相关论文
共 50 条
  • [31] FEATURES OF SEXUAL NERVOUSNESS OF MEN AND WOMEN
    Hupalovska, Viktoriya
    Kocherhina, Iryna
    JOURNAL OF EDUCATION CULTURE AND SOCIETY, 2020, 11 (02): : 199 - 210
  • [32] SEXUAL HARASSMENT PROCLIVITIES IN MEN AND WOMEN
    BARTLING, CA
    EISENMAN, R
    BULLETIN OF THE PSYCHONOMIC SOCIETY, 1993, 31 (03) : 189 - 192
  • [33] Comparison of Sexual Satisfaction in Men and Women
    Hurtado De Mendoza Zabalgoitia, Maria Teresa
    Contreras San Juan, Gabriel
    INTERNATIONAL JOURNAL OF SEXUAL HEALTH, 2019, 31 : A505 - A506
  • [34] Sexual Dysfuctions in Homosexual Men and Women
    Hacioglu, Munevver
    Cakmak, Aysen Cosut
    Yildirim, Ejder Akgun
    NOROPSIKIYATRI ARSIVI-ARCHIVES OF NEUROPSYCHIATRY, 2011, 48 : 39 - 45
  • [35] Sexual Functioning in Women and Men with Fibromyalgia
    Rico-Villademoros, Fernando
    Calandre, Elena P.
    Rodriguez-Lopez, Carmen M.
    Garcia-Carrillo, Jocelyne
    Ballesteros, Javier
    Hidalgo-Tallon, Javier
    Garcia-Leiva, Juan M.
    JOURNAL OF SEXUAL MEDICINE, 2012, 9 (02): : 542 - 549
  • [36] PTSD and Sexual Dysfunction in Men and Women
    Yehuda, Rachel
    Lehrner, Amy
    Rosenbaum, Talli Y.
    JOURNAL OF SEXUAL MEDICINE, 2015, 12 (05): : 1107 - 1119
  • [37] Schopenhauer on women, men, and sexual love
    Atwell, JE
    MIDWEST QUARTERLY-A JOURNAL OF CONTEMPORARY THOUGHT, 1997, 38 (02): : 143 - 157
  • [38] SEXUAL DYSFUNCTION IN COLLEGE MEN AND WOMEN
    WERNER, A
    AMERICAN JOURNAL OF PSYCHIATRY, 1975, 132 (02): : 164 - 169
  • [39] Effects of Alcohol on Tests of Executive Functioning in Men and Women: A Dose Response Examination
    Guillot, Casey R.
    Fanning, Jennifer R.
    Bullock, Joshua S.
    McCloskey, Michael S.
    Berman, Mitchell E.
    EXPERIMENTAL AND CLINICAL PSYCHOPHARMACOLOGY, 2010, 18 (05) : 409 - 417
  • [40] Effect of Alcohol Dose on Deliberate Self-Harm in Men and Women
    Berman, Mitchell E.
    Fanning, Jennifer R.
    Guillot, Casey R.
    Marsic, Angelika
    Bullock, Joshua
    Nadorff, Michael R.
    McCloskey, Michael S.
    JOURNAL OF CONSULTING AND CLINICAL PSYCHOLOGY, 2017, 85 (09) : 854 - 861