Structural basis of LaDR5, a novel agonistic anti-death receptor 5 (DR5) monoclonal antibody, to inhibit DR5/TRAIL complex formation

被引：0
|
作者：
Chunxia Qiao
Meiyun Hu
Leiming Guo
Ming Lv
Zhou Lin
Jing Geng
Xiaoling Lang
Xinying Li
Yan Li
Yuanfang Ma
Jiannan Feng
Beifen Shen
机构：
[1] Institute of Basic Medical Sciences,Department of Immunology
[2] Henan University,Laboratory of Cellular and Molecular Immunology, Institute of Immunology
来源：
BMC Immunology | / 13卷
关键词：
TRAIL; Death receptor 5; Monoclonal antibody; Apoptosis; Breast cancer;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [21] Requirement of both isoforms of TRAIL-R2 (DR5) in death receptor signaling
    Peters, Kristi
    Yang, Ke
    DeVecchio, Jennifer
    Humphreys, Robin
    Houghton, Janet
    CANCER RESEARCH, 2009, 69
  • [22] The Characteristic of an Anti-Human DR5 Antibody A6
    Yugang Wang1
    2Lab of Cellular and Molecular Immunology
    Cellular&MolecularImmunology, 2008, (03) : 183 - 188
  • [23] The characteristic of an anti-human DR5 antibody A6
    Wang, Yugang
    Zhao, Kuipeng
    Chen, Jugao
    Zhangi, Jiyan
    Yu, Ming
    Li, Yan
    Shen, Beifen
    CELLULAR & MOLECULAR IMMUNOLOGY, 2008, 5 (03) : 183 - 188
  • [24] Targeting of keloid with TRAIL and TRAIL-R2/DR5
    Sun, Pengfei
    Hu, Zhensheng
    Pan, Bo
    Lu, Xiaosheng
    JOURNAL OF DERMATOLOGICAL TREATMENT, 2021, 32 (08) : 957 - 964
  • [25] The Characteristic of an Anti-Human DR5 Antibody A6
    Yugang Wang
    Kunpeng Zhao
    Jugao Chen
    Jiyan Zhang
    Ming Yu
    Yan Li
    Beifen Shen
    Cellular & Molecular Immunology, 2008, 5 : 183 - 188
  • [26] Expression of TRAIL and its receptor DR5 and their significance in acute leukemia cells
    Chen, S. M.
    Sun, H.
    Liu, Y. F.
    Ma, J.
    Zhang, Q. T.
    Zhu, J.
    Li, T.
    GENETICS AND MOLECULAR RESEARCH, 2015, 14 (04) : 18562 - 18568
  • [27] Combinatorial Screening of Peptides, Specific Ligands of Death Receptor DR5
    V. M. Ukrainskaya
    A. V. Stepanov
    A. A. Belogurov
    A. G. Gabibov
    Bulletin of Experimental Biology and Medicine, 2017, 163 : 381 - 384
  • [28] Combinatorial Screening of Peptides, Specific Ligands of Death Receptor DR5
    Ukrainskaya, V. M.
    Stepanov, A. V.
    Belogurov, A. A., Jr.
    Gabibov, A. G.
    BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE, 2017, 163 (03) : 381 - 384
  • [29] Mutation of the DR5/TRAIL receptor 2 gene is infrequent in hepatocellular carcinoma
    Jeng, YM
    Hsu, HC
    CANCER LETTERS, 2002, 181 (02) : 205 - 208
  • [30] Cooperation of the Agonistic DR5 Antibody Apomab with Chemotherapy to Inhibit Orthotopic Lung Tumor Growth and Improve Survival
    Jin, Hongkui
    Yang, Renhui
    Ross, Jed
    Fong, Sharon
    Carano, Richard
    Totpal, Klara
    Lawrence, David
    Zheng, Zhong
    Koeppen, Hartmut
    Stern, Howard
    Schwall, Ralph
    Ashkenazi, Avi
    CLINICAL CANCER RESEARCH, 2008, 14 (23) : 7733 - 7740
12345