Myeloid-derived suppressor cells and their role in pancreatic cancer

被引:0
|
作者
M Pergamo
G Miller
机构
[1] S. Arthur Localio Laboratory,Department of Cell Biology
[2] New York University School of Medicine,undefined
来源
Cancer Gene Therapy | 2017年 / 24卷
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摘要
Pancreatic cancer is a devastating disease and ranks as the third most common cause of cancer-related death. Like many cancers, there has been increased interest in the role of the immune system in the progression and development of pancreatic cancer. In particular, immunosuppression within the tumor microenvironment (TME) is thought to impair the host’s antitumor response. In this article, we review myeloid-derived suppressor cells and their contribution to this immunosuppression within the pancreatic TME.
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页码:100 / 105
页数:5
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