Microbial production of poly-γ-glutamic acid

被引:0
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作者
Sarote Sirisansaneeyakul
Mingfeng Cao
Nuttawut Kongklom
Chaniga Chuensangjun
Zhongping Shi
Yusuf Chisti
机构
[1] Kasetsart University,Department of Biotechnology, Faculty of Agro
[2] Kasetsart University,Industry
[3] Iowa State University,Center for Advanced Studies in Tropical Natural Resources (CASTNAR), National Research University
[4] Jiangnan University,Kasetsart University (NRU
[5] Massey University,KU)
关键词
spp.; Biopolymers; Fermentation; Polypeptides; Poly-γ-glutamic acid;
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摘要
Poly-γ-glutamic acid (γ-PGA) is a natural, biodegradable and water-soluble biopolymer of glutamic acid. This review is focused on nonrecombinant microbial production of γ-PGA via fermentation processes. In view of its commercial importance, the emphasis is on l-glutamic acid independent producers (i.e. microorganisms that do not require feeding with the relatively expensive amino acid l-glutamic acid to produce γ-PGA), but glutamic acid dependent production is discussed for comparison. Strategies for improving production, reducing costs and using renewable feedstocks are discussed.
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