Synthesis of 7-alkyl-4-amino-7H-pyrrolo-[2,3-d]pyrimidine-6-carboxylic acids

被引：0

作者：

E. V. Verves

A. V. Kucher

L. V. Muzychka

O. B. Smolii

机构：

[1] National Academy of Sciences of Ukraine,Institute of Bioorganic Chemistry and Petrochemistry

来源：

Chemistry of Heterocyclic Compounds | 2013年 / 48卷

关键词：

ethyl ; -alkylglycinate; pyrimido[5',4':4,5]pyrrolo[2,1-; ][1,4]oxazine; 7; -pyrrolo[2,3-; ]-pyrimidine; cyclization;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Two variants are discussed for the synthesis of ethyl N-alkyl-N-(6-amino-5-formylpyrimidin-4-yl)-glycinate derivatives, which are converted by intramolecular cyclization under the influence of sodium methoxide to give methyl 7H-pyrrolo[2,3-d]pyrimidine-6-carboxylates. New derivatives of pyrimido- [5',4':4,5]pyrrolo[2,1-c][1,4]oxazines containing 3-chloropropyl groups at position 8 have been prepared.

引用

页码：1844 / 1852

页数：8

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